PAX_I49A1
ID PAX_I49A1 Reviewed; 252 AA.
AC P0CK82;
DT 03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2012, sequence version 1.
DT 02-JUN-2021, entry version 33.
DE RecName: Full=Protein PA-X;
GN Name=PA;
OS Influenza A virus (strain A/Duck/Germany/1949 H10N7).
OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC Insthoviricetes; Articulavirales; Orthomyxoviridae; Alphainfluenzavirus.
OX NCBI_TaxID=382838;
OH NCBI_TaxID=8782; Aves.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=16439620; DOI=10.1126/science.1121586;
RA Obenauer J.C., Denson J., Mehta P.K., Su X., Mukatira S., Finkelstein D.B.,
RA Xu X., Wang J., Ma J., Fan Y., Rakestraw K.M., Webster R.G., Hoffmann E.,
RA Krauss S., Zheng J., Zhang Z., Naeve C.W.;
RT "Large-scale sequence analysis of avian influenza isolates.";
RL Science 311:1576-1580(2006).
CC -!- FUNCTION: May play a role in the modulation of host immune response.
CC {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Ribosomal frameshifting; Named isoforms=2;
CC Name=PA-X;
CC IsoId=P0CK82-1; Sequence=Displayed;
CC Name=PA;
CC IsoId=Q0A441-1; Sequence=External;
CC -!- SIMILARITY: Belongs to the influenza viruses PA-X family.
CC {ECO:0000305}.
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DR EMBL; CY014676; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR SMR; P0CK82; -.
DR Proteomes; UP000008217; Genome.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR Gene3D; 3.40.91.90; -; 1.
DR InterPro; IPR001009; PA/PA-X.
DR InterPro; IPR038372; PA/PA-X_sf.
DR Pfam; PF00603; Flu_PA; 1.
PE 3: Inferred from homology;
KW Ribosomal frameshifting.
FT CHAIN 1..252
FT /note="Protein PA-X"
FT /id="PRO_0000419365"
FT REGION 202..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 252 AA; 29376 MW; 2B2BB85C55DCA616 CRC64;
MEDFVRQCFN PMIVELAEKA MKEYGEDPKI ETNKFAAICT HLEVCFMYSD FHFIDERGES
IIVESGDPNA LLKHRFEIIE GRDRTMAWTV VNSICNTTRV EKPKFLPDLY DYKENRFIEI
GVTRREVHIY YLEKANKIKS EKTHIHIFSF TGEEMATKAD YTLDEESRAR IKTRLFTIRQ
EMASRGLWDS FVSPREAKRQ LKKDLKSQEP CAGSPTKVSH RTSPALKTLE PMWMDSSRTA
ALRASFLKCP KK