ID   PAX_I56A2               Reviewed;         252 AA.
AC   P0CK81;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 1.
DT   02-JUN-2021, entry version 25.
DE   RecName: Full=Protein PA-X;
GN   Name=PA;
OS   Influenza A virus (strain A/Duck/England/1/1956 H11N6).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC   Insthoviricetes; Articulavirales; Orthomyxoviridae; Alphainfluenzavirus.
OX   NCBI_TaxID=383550;
OH   NCBI_TaxID=8782; Aves.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=16439620; DOI=10.1126/science.1121586;
RA   Obenauer J.C., Denson J., Mehta P.K., Su X., Mukatira S., Finkelstein D.B.,
RA   Xu X., Wang J., Ma J., Fan Y., Rakestraw K.M., Webster R.G., Hoffmann E.,
RA   Krauss S., Zheng J., Zhang Z., Naeve C.W.;
RT   "Large-scale sequence analysis of avian influenza isolates.";
RL   Science 311:1576-1580(2006).
CC   -!- FUNCTION: May play a role in the modulation of host immune response.
CC       {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Ribosomal frameshifting; Named isoforms=2;
CC       Name=PA-X;
CC         IsoId=P0CK81-1; Sequence=Displayed;
CC       Name=PA;
CC         IsoId=Q0A430-1; Sequence=External;
CC   -!- SIMILARITY: Belongs to the influenza viruses PA-X family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CY014684; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR   SMR; P0CK81; -.
DR   Proteomes; UP000155465; Genome.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR   Gene3D; 3.40.91.90; -; 1.
DR   InterPro; IPR001009; PA/PA-X.
DR   InterPro; IPR038372; PA/PA-X_sf.
DR   Pfam; PF00603; Flu_PA; 1.
PE   3: Inferred from homology;
KW   Ribosomal frameshifting.
FT   CHAIN           1..252
FT                   /note="Protein PA-X"
FT                   /id="PRO_0000419364"
FT   REGION          202..223
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   252 AA;  29337 MW;  766B7BDDA6F5C8A5 CRC64;
     MEDFVRQCFN PMIVELAEKA MKEYGEDPKI ETNKFAAICT HLEVCFMYSD FHFIDERGES
     IIVEPGDPNA LLKHRFEIIE GRDRTVAWTV VNSICNTTGV EKPKFLPDLY DYKENRFIEI
     GVTRREVHIY YLEKANKIKS EKTHIHIFSF TGEEMATKAD YTLDEESRAR IKTRLFTIRQ
     EMASRGLWDS FVNPREAKRQ LKKDLRSQEP CAGSPTKVSH RTSPALKTLE PMWMDSNRTA
     ALRASFLKCP KK