ID   PAX_I66A1               Reviewed;         252 AA.
AC   P0DJV9;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 1.
DT   10-FEB-2021, entry version 25.
DE   RecName: Full=Protein PA-X;
GN   Name=PA;
OS   Influenza A virus (strain A/Turkey/Wisconsin/1/1966 H9N2).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC   Insthoviricetes; Articulavirales; Orthomyxoviridae; Alphainfluenzavirus.
OX   NCBI_TaxID=385620;
OH   NCBI_TaxID=8782; Aves.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=16026813; DOI=10.1016/j.virol.2005.06.025;
RA   Li C., Yu K., Tian G., Yu D., Liu L., Jing B., Ping J., Chen H.;
RT   "Evolution of H9N2 influenza viruses from domestic poultry in Mainland
RT   China.";
RL   Virology 340:70-83(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=16439620; DOI=10.1126/science.1121586;
RA   Obenauer J.C., Denson J., Mehta P.K., Su X., Mukatira S., Finkelstein D.B.,
RA   Xu X., Wang J., Ma J., Fan Y., Rakestraw K.M., Webster R.G., Hoffmann E.,
RA   Krauss S., Zheng J., Zhang Z., Naeve C.W.;
RT   "Large-scale sequence analysis of avian influenza isolates.";
RL   Science 311:1576-1580(2006).
CC   -!- FUNCTION: May play a role in the modulation of host immune response.
CC       {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Ribosomal frameshifting; Named isoforms=2;
CC       Name=PA-X;
CC         IsoId=P0DJV9-1; Sequence=Displayed;
CC       Name=PA;
CC         IsoId=Q0A452-1; Sequence=External;
CC   -!- SIMILARITY: Belongs to the influenza viruses PA-X family.
CC       {ECO:0000305}.
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DR   EMBL; DQ067442; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR   EMBL; CY014668; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR   SMR; P0DJV9; -.
DR   Proteomes; UP000115522; Genome.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR   Gene3D; 3.40.91.90; -; 1.
DR   InterPro; IPR001009; PA/PA-X.
DR   InterPro; IPR038372; PA/PA-X_sf.
DR   Pfam; PF00603; Flu_PA; 1.
PE   3: Inferred from homology;
KW   Ribosomal frameshifting.
FT   CHAIN           1..252
FT                   /note="Protein PA-X"
FT                   /id="PRO_0000419422"
FT   CONFLICT        73
FT                   /note="K -> Q (in Ref. 1; DQ067442)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        168
FT                   /note="R -> K (in Ref. 1; DQ067442)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        180
FT                   /note="Q -> P (in Ref. 1; DQ067442)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        206
FT                   /note="K -> R (in Ref. 1; DQ067442)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        209..210
FT                   /note="EQ -> DK (in Ref. 1; DQ067442)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        221
FT                   /note="R -> G (in Ref. 1; DQ067442)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   252 AA;  29347 MW;  FA5A269B5757D816 CRC64;
     MEDFVRQCFN PMIVELAEKA MKEYGEDPKI ETNKFAAICT HLEVCFMYSD FHFIDERGES
     IIVESGDPNA LLKHRFEIIE GRDRTMAWTV VNSICNTTGV EKPKFLPDLY DYKENRFIEI
     GVTRREVHIY YLEKANKVKS EKTHIHIFSF TGEEMATKAD YTLDEESRAR IKTRLFTIRQ
     EMASRGLWDS FVSPREAKRQ LKKDLKSQEQ CAGLPTKVSH RTSPALKTLE PMWMDSNRTA
     ALRASFLKCP KK