ID   PAX_I73A5               Reviewed;         252 AA.
AC   P0DJT9;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 1.
DT   07-OCT-2020, entry version 20.
DE   RecName: Full=Protein PA-X;
GN   Name=PA;
OS   Influenza A virus (strain A/Port Chalmers/1/1973 H3N2).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC   Insthoviricetes; Articulavirales; Orthomyxoviridae; Alphainfluenzavirus.
OX   NCBI_TaxID=385624;
OH   NCBI_TaxID=8782; Aves.
OH   NCBI_TaxID=9721; Cetacea (whales).
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=9709; Phocidae (true seals).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA   Spiro D., Ghedin E., Sengamalay N., Halpin R., Boyne A., Zaborsky J.,
RA   Feldblyum T., Subbu V., Sparenborg J., Shumway M., Sitz J., Katzel D.,
RA   Koo H., Salzberg S.L., Griesemer S., St George K., Bennett R., Taylor J.,
RA   Bennink J.R., Yewdell J.W., Bao Y., Bolotov P., Dernovoy D., Kiryutin B.,
RA   Lipman D.J., Tatusova T.;
RT   "The NIAID influenza genome sequencing project.";
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in the modulation of host immune response.
CC       {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Ribosomal frameshifting; Named isoforms=2;
CC       Name=PA-X;
CC         IsoId=P0DJT9-1; Sequence=Displayed;
CC       Name=PA;
CC         IsoId=Q1PUD2-1; Sequence=External;
CC   -!- SIMILARITY: Belongs to the influenza viruses PA-X family.
CC       {ECO:0000305}.
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DR   EMBL; CY009353; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR   SMR; P0DJT9; -.
DR   Proteomes; UP000133870; Genome.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR   Gene3D; 3.40.91.90; -; 1.
DR   InterPro; IPR001009; PA/PA-X.
DR   InterPro; IPR038372; PA/PA-X_sf.
DR   Pfam; PF00603; Flu_PA; 1.
PE   3: Inferred from homology;
KW   Ribosomal frameshifting.
FT   CHAIN           1..252
FT                   /note="Protein PA-X"
FT                   /id="PRO_0000419402"
SQ   SEQUENCE   252 AA;  29377 MW;  329480D592B3AF0D CRC64;
     MEDFVRQCFN PMVVELAEKA MKEYGEDLKI ETNKFAAICT HLEVCFMYSD FHFINEQGES
     IVVELDDPNA LLKHRFEIIE GRDRTMAWTV VNSICNTTGA EKPKFLPDLY DYKENRFIEI
     GVTRREVHIY YLEKANKIKS ENTHIHIFSF TGEEMATKAD YTLDEESRAR IKTRLFTIRQ
     EMANRGLWDS FVSPKEAKKQ LKKDLKSQEL CAGLPTKVSR RTSPALRILE PMWMDSNRTA
     ALRASFLKCP KK