PAX_I85A3
ID PAX_I85A3 Reviewed; 252 AA.
AC P0CK77;
DT 03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2012, sequence version 1.
DT 02-DEC-2020, entry version 19.
DE RecName: Full=Protein PA-X;
GN Name=PA;
OS Influenza A virus (strain A/Chicken/Victoria/1/1985 H7N7).
OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC Insthoviricetes; Articulavirales; Orthomyxoviridae; Alphainfluenzavirus.
OX NCBI_TaxID=402520;
OH NCBI_TaxID=8782; Aves.
OH NCBI_TaxID=9796; Equus caballus (Horse).
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9709; Phocidae (true seals).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=16439620; DOI=10.1126/science.1121586;
RA Obenauer J.C., Denson J., Mehta P.K., Su X., Mukatira S., Finkelstein D.B.,
RA Xu X., Wang J., Ma J., Fan Y., Rakestraw K.M., Webster R.G., Hoffmann E.,
RA Krauss S., Zheng J., Zhang Z., Naeve C.W.;
RT "Large-scale sequence analysis of avian influenza isolates.";
RL Science 311:1576-1580(2006).
CC -!- FUNCTION: May play a role in the modulation of host immune response.
CC {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Ribosomal frameshifting; Named isoforms=2;
CC Name=PA-X;
CC IsoId=P0CK77-1; Sequence=Displayed;
CC Name=PA;
CC IsoId=Q0A2Q7-1; Sequence=External;
CC -!- SIMILARITY: Belongs to the influenza viruses PA-X family.
CC {ECO:0000305}.
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DR EMBL; CY015024; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR SMR; P0CK77; -.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR Gene3D; 3.40.91.90; -; 1.
DR InterPro; IPR001009; PA/PA-X.
DR InterPro; IPR038372; PA/PA-X_sf.
DR Pfam; PF00603; Flu_PA; 1.
PE 3: Inferred from homology;
KW Ribosomal frameshifting.
FT CHAIN 1..252
FT /note="Protein PA-X"
FT /id="PRO_0000419360"
SQ SEQUENCE 252 AA; 29296 MW; 74EC5E11735DBC5C CRC64;
MEDFVRQCFN PIIVELAEKA MKEYGEDPKI ETNKFAAICT HLEVCFMYSD FHFIDERGES
IIVESGDPNA LLKHRFEIIE GRDRTMAWTV VNSICNTTGV EKPKFLPDLY DYKENRFVEI
GVTRREVHIY YLEKANKIKS EKTHIHIFSF TGEEMATKAD YTLDEESRAR IKTRLFTIRQ
EMASRGLWDS FVSPREAKKQ LKKDLKLQEP CAGLPTKVSH RTSPALKTLE PMWMDSNRTA
ALRASFLKCP KK