PA_I82A2
ID PA_I82A2 Reviewed; 75 AA.
AC P26145;
DT 01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1992, sequence version 1.
DT 07-APR-2021, entry version 72.
DE RecName: Full=Polymerase acidic protein;
DE AltName: Full=RNA-directed RNA polymerase subunit P2;
DE Flags: Fragment;
GN Name=PA;
OS Influenza A virus (strain A/Camel/Mongolia/1982 H1N1).
OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC Insthoviricetes; Articulavirales; Orthomyxoviridae; Alphainfluenzavirus.
OX NCBI_TaxID=387191;
OH NCBI_TaxID=8782; Aves.
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=8249279; DOI=10.1006/viro.1993.1629;
RA Yamnikova S.S., Mandler J., Bekh-Ochir Z.H., Dachtzeren P., Ludwig S.,
RA Lvov D.K., Scholtissek C.;
RT "A reassortant H1N1 influenza A virus caused fatal epizootics among camels
RT in Mongolia.";
RL Virology 197:558-563(1993).
CC -!- FUNCTION: Implicated in endonuclease cleavage of capped RNA primers.
CC Displays an elongation factor activity in viral RNA synthesis.
CC Dispensable for viral transcription, but not replication.
CC -!- SUBUNIT: Influenza RNA polymerase is composed of three subunits: PB1,
CC PB2 and PA.
CC -!- PTM: Phosphorylated on serines and threonines by host kinases,
CC including human casein kinase II. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the influenza viruses PA family. {ECO:0000305}.
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DR EMBL; M73974; AAA16909.1; -; mRNA.
DR SMR; P26145; -.
DR MEROPS; S62.001; -.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR InterPro; IPR001009; PA/PA-X.
DR Pfam; PF00603; Flu_PA; 1.
PE 2: Evidence at transcript level;
KW Phosphoprotein.
FT CHAIN <1..>75
FT /note="Polymerase acidic protein"
FT /id="PRO_0000078780"
FT NON_TER 1
FT NON_TER 75
SQ SEQUENCE 75 AA; 8503 MW; CAABE9473AD4A4D4 CRC64;
TDSSWIELDE IGEDVAPIEH IASMRRNYFT SEVSHCRATE YIMKGVYINT ALLNASCAAM
DDFQLIPMIS KCRTK