PBAN_MAMBR
ID PBAN_MAMBR Reviewed; 155 AA.
AC O45027;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 25-MAY-2022, entry version 60.
DE RecName: Full=PBAN-type neuropeptides;
DE AltName: Full=Pheromone/pyrokinin biosynthesis-activating neuropeptide;
DE Contains:
DE RecName: Full=Diapause hormone homolog;
DE Short=DH;
DE Contains:
DE RecName: Full=Alpha-SG neuropeptide;
DE Short=Mab-alpha-NP;
DE Contains:
DE RecName: Full=Beta-SG neuropeptide;
DE Short=Mab-beta-NP;
DE AltName: Full=Pyrokinin-1;
DE Contains:
DE RecName: Full=Pheromone biosynthesis-activating neuropeptide;
DE Short=Mab-PBAN;
DE AltName: Full=Pyrokinin-2;
DE Contains:
DE RecName: Full=Gamma-SG neuropeptide;
DE Short=Mab-gamma-NP;
DE AltName: Full=Pyrokinin-3;
DE Flags: Precursor; Fragment;
GN Name=PBAN;
OS Mamestra brassicae (Cabbage moth).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC Noctuidae; Hadeninae; Mamestra.
OX NCBI_TaxID=55057;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=9684333; DOI=10.1016/s0965-1748(98)00017-4;
RA Jacquin-Joly E., Burnet M., Francois M.-C., Ammar D., Nagnan-Meillour P.,
RA Descoins C.;
RT "cDNA cloning and sequence determination of the pheromone biosynthesis
RT activating neuropeptide of Mamestra brassicae: a new member of the PBAN
RT family.";
RL Insect Biochem. Mol. Biol. 28:251-258(1998).
CC -!- FUNCTION: A hormone that controls sex pheromone production in females
CC and pheromone responsiveness in male. Also mediates visceral muscle
CC contractile activity (myotropic activity) (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- MISCELLANEOUS: Juvenile hormone seems to allow PBAN release, which then
CC induces pheromone biosynthesis. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the pyrokinin family. {ECO:0000305}.
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DR EMBL; AF044079; AAC02094.1; -; mRNA.
DR AlphaFoldDB; O45027; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005184; F:neuropeptide hormone activity; IEA:InterPro.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0042811; P:pheromone biosynthetic process; IEA:InterPro.
DR GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
DR InterPro; IPR008730; PBAN.
DR InterPro; IPR001484; Pyrokinin_CS.
DR Pfam; PF05874; PBAN; 1.
DR PROSITE; PS00539; PYROKININ; 3.
PE 2: Evidence at transcript level;
KW Amidation; Cleavage on pair of basic residues; Hormone; Neuropeptide;
KW Pheromone response; Secreted.
FT PEPTIDE <1..8
FT /note="Diapause hormone homolog"
FT /evidence="ECO:0000255"
FT /id="PRO_0000029943"
FT PROPEP 12..55
FT /id="PRO_0000029944"
FT PEPTIDE 58..64
FT /note="Alpha-SG neuropeptide"
FT /evidence="ECO:0000255"
FT /id="PRO_0000029945"
FT PEPTIDE 67..84
FT /note="Beta-SG neuropeptide"
FT /evidence="ECO:0000255"
FT /id="PRO_0000029946"
FT PEPTIDE 88..120
FT /note="Pheromone biosynthesis-activating neuropeptide"
FT /id="PRO_0000029947"
FT PEPTIDE 123..130
FT /note="Gamma-SG neuropeptide"
FT /evidence="ECO:0000255"
FT /id="PRO_0000029948"
FT PROPEP 133..155
FT /id="PRO_0000029949"
FT MOD_RES 8
FT /note="Isoleucine amide"
FT /evidence="ECO:0000250"
FT MOD_RES 64
FT /note="Leucine amide"
FT /evidence="ECO:0000250"
FT MOD_RES 84
FT /note="Leucine amide"
FT /evidence="ECO:0000250"
FT MOD_RES 120
FT /note="Leucine amide"
FT /evidence="ECO:0000250"
FT MOD_RES 130
FT /note="Leucine amide"
FT /evidence="ECO:0000250"
FT NON_TER 1
SQ SEQUENCE 155 AA; 18096 MW; 78547503164A9D06 CRC64;
GLWFGPRIGK RSLRMATEDN RQAFFKLLEA ADALKYYYDQ LPYEMQADEP ETRVTKKVIF
TPKLGRSLAY DDKVFENVEF TPRLGRRLAD DMPATPADQE MYRPDPEQID SRTKYFSPRL
GRTMNFSPRL GRELAYEMVP SKIRVVRSTN KTQST
