PBAS_MOUSE
ID PBAS_MOUSE Reviewed; 174 AA.
AC O08976;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 2.
DT 03-AUG-2022, entry version 144.
DE RecName: Full=Probasin;
DE Short=PB;
DE Flags: Precursor;
GN Name=Pbsn; Synonyms=Prbs;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=C57BL/6J; TISSUE=Prostate;
RA Johnson M.A., Greenberg N.M.;
RT "Cloning and characterization of the mouse probasin cDNA.";
RL Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the calycin superfamily. Lipocalin family.
CC {ECO:0000305}.
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DR EMBL; AF005204; AAC01954.1; -; mRNA.
DR CCDS; CCDS30249.1; -.
DR RefSeq; NP_059499.1; NM_017471.2.
DR AlphaFoldDB; O08976; -.
DR SMR; O08976; -.
DR STRING; 10090.ENSMUSP00000000003; -.
DR iPTMnet; O08976; -.
DR PhosphoSitePlus; O08976; -.
DR PaxDb; O08976; -.
DR PRIDE; O08976; -.
DR ProteomicsDB; 294021; -.
DR DNASU; 54192; -.
DR Ensembl; ENSMUST00000000003; ENSMUSP00000000003; ENSMUSG00000000003.
DR GeneID; 54192; -.
DR KEGG; mmu:54192; -.
DR UCSC; uc009tqr.1; mouse.
DR CTD; 54192; -.
DR MGI; MGI:1860484; Pbsn.
DR VEuPathDB; HostDB:ENSMUSG00000000003; -.
DR eggNOG; ENOG502TDZD; Eukaryota.
DR GeneTree; ENSGT01050000244868; -.
DR InParanoid; O08976; -.
DR OMA; FRHIECM; -.
DR OrthoDB; 1357921at2759; -.
DR PhylomeDB; O08976; -.
DR TreeFam; TF338197; -.
DR BioGRID-ORCS; 54192; 1 hit in 71 CRISPR screens.
DR ChiTaRS; Pbsn; mouse.
DR PRO; PR:O08976; -.
DR Proteomes; UP000000589; Chromosome X.
DR RNAct; O08976; protein.
DR Bgee; ENSMUSG00000000003; Expressed in prostate gland ventral lobe and 4 other tissues.
DR ExpressionAtlas; O08976; baseline and differential.
DR Genevisible; O08976; MM.
DR GO; GO:0005576; C:extracellular region; IDA:MGI.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR GO; GO:0036094; F:small molecule binding; IEA:InterPro.
DR Gene3D; 2.40.128.20; -; 1.
DR InterPro; IPR012674; Calycin.
DR InterPro; IPR002345; Lipocalin.
DR InterPro; IPR000566; Lipocln_cytosolic_FA-bd_dom.
DR InterPro; IPR002448; OBP-like.
DR PANTHER; PTHR11430; PTHR11430; 1.
DR Pfam; PF00061; Lipocalin; 1.
DR PRINTS; PR01173; ODORANTBNDNG.
DR SUPFAM; SSF50814; SSF50814; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Reference proteome; Secreted; Signal.
FT SIGNAL 1..18
FT /evidence="ECO:0000250"
FT CHAIN 19..174
FT /note="Probasin"
FT /id="PRO_0000017954"
FT DISULFID 77..168
FT /evidence="ECO:0000250"
SQ SEQUENCE 174 AA; 20372 MW; 62CE0B046F7106C3 CRC64;
MMRVIILLLT LHVLGVSSVM SLKKKIDGPW QTIYLAASTM EKINEGSPLR TYFRHILCGR
RCNQVYLYFF IKKGTKCQLY KVIGRKKQEV YYAQYEGSIA FMLKMVNEKI LLFHYFNKNR
RNDVTRVAGV LAKGKQLNKE EMTEFMNLVE EMGIEEENVQ RIMDTDNCPS KIKP