PBGP9_SOLMC
ID PBGP9_SOLMC Reviewed; 153 AA.
AC A9LKF6; A9LKF5; Q7KF15; Q8WRQ1;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-JUN-2008, sequence version 2.
DT 25-MAY-2022, entry version 34.
DE RecName: Full=Pheromone-binding protein Gp-9;
DE Short=PBP;
DE AltName: Full=Putative odorant-binding protein Gp-9;
DE Flags: Precursor;
GN Name=Gp-9 {ECO:0000312|EMBL:AAL51121.1};
OS Solenopsis macdonaghi (Fire ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Solenopsis.
OX NCBI_TaxID=176595;
RN [1] {ECO:0000305, ECO:0000312|EMBL:AAL51121.1}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELES B AND B'), AND VARIANTS THR-39;
RP GLY-42; ASP-45; ILE-95; ALA-136; ILE-139 AND ALA-152.
RX PubMed=11711637; DOI=10.1126/science.1065247;
RA Krieger M.J.B., Ross K.G.;
RT "Identification of a major gene regulating complex social behavior.";
RL Science 295:328-332(2002).
RN [2] {ECO:0000312|EMBL:ABX25634.1}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Pi-80 {ECO:0000312|EMBL:ABX25633.1}, and
RC Pu-37 {ECO:0000312|EMBL:ABX25634.1};
RX PubMed=17987107; DOI=10.1371/journal.pone.0001088;
RA Gotzek D., Shoemaker D.D., Ross K.G.;
RT "Molecular variation at a candidate gene implicated in the regulation of
RT fire ant social behavior.";
RL PLoS ONE 2:E1088-E1088(2007).
CC -!- FUNCTION: Colony queen number, a major feature of social organization,
CC is associated with worker genotype for Gp-9. Colonies are headed by
CC either a single reproductive queen (monogyne form) or multiple queens
CC (polygyne form). Differences in worker Gp-9 genotypes between social
CC forms may cause differences in workers' abilities to recognize queens
CC and regulate their numbers (By similarity).
CC {ECO:0000250|UniProtKB:Q8WP90}.
CC -!- SUBUNIT: Homodimer. {ECO:0000250|UniProtKB:P20797}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- POLYMORPHISM: Allele B is shown, polygyne population from Argentina.
CC {ECO:0000269|PubMed:11711637}.
CC -!- SIMILARITY: Belongs to the PBP/GOBP family. {ECO:0000255}.
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DR EMBL; AF427895; AAL51121.1; -; Genomic_DNA.
DR EMBL; AF427901; AAL51127.1; -; Genomic_DNA.
DR EMBL; EU220054; ABX25633.1; -; Genomic_DNA.
DR EMBL; EU220055; ABX25634.1; -; Genomic_DNA.
DR AlphaFoldDB; A9LKF6; -.
DR SMR; A9LKF6; -.
DR GO; GO:0005615; C:extracellular space; ISS:UniProtKB.
DR GO; GO:0005550; F:pheromone binding; IEA:UniProtKB-KW.
DR GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
DR GO; GO:0035176; P:social behavior; ISS:UniProtKB.
DR Gene3D; 1.10.238.20; -; 1.
DR InterPro; IPR006170; PBP/GOBP.
DR InterPro; IPR036728; PBP_GOBP_sf.
DR InterPro; IPR022354; Pheromone-bd_protein_Gp-9.
DR Pfam; PF01395; PBP_GOBP; 1.
DR PRINTS; PR02007; ODORANTBPGP9.
DR SUPFAM; SSF47565; SSF47565; 1.
PE 3: Inferred from homology;
KW Behavior; Disulfide bond; Pheromone response; Pheromone-binding; Secreted;
KW Signal; Transport.
FT SIGNAL 1..19
FT /evidence="ECO:0000250|UniProtKB:Q8WP90"
FT CHAIN 20..153
FT /note="Pheromone-binding protein Gp-9"
FT /evidence="ECO:0000250|UniProtKB:Q8WP90"
FT /id="PRO_5000061697"
FT DISULFID 37..77
FT /evidence="ECO:0000250|UniProtKB:P20797"
FT DISULFID 73..129
FT /evidence="ECO:0000250|UniProtKB:P20797"
FT DISULFID 118..138
FT /evidence="ECO:0000250|UniProtKB:P20797"
FT VARIANT 39
FT /note="A -> T (in allele b')"
FT /evidence="ECO:0000269|PubMed:11711637"
FT VARIANT 42
FT /note="S -> G (in allele b')"
FT /evidence="ECO:0000269|PubMed:11711637"
FT VARIANT 45
FT /note="E -> D (in allele b')"
FT /evidence="ECO:0000269|PubMed:11711637"
FT VARIANT 95
FT /note="M -> I (in allele b')"
FT /evidence="ECO:0000269|PubMed:11711637"
FT VARIANT 136
FT /note="V -> A (in allele b')"
FT /evidence="ECO:0000269|PubMed:11711637"
FT VARIANT 139
FT /note="V -> I (in allele b')"
FT /evidence="ECO:0000269|PubMed:11711637"
FT VARIANT 152
FT /note="G -> A (in allele b')"
FT /evidence="ECO:0000269|PubMed:11711637"
SQ SEQUENCE 153 AA; 16847 MW; A1439A98AEBE3560 CRC64;
MKTFVLHIFI FALVAFASAS RDSARKIGSQ YDNYATCLAE HSLTEDDIFS IGEVSSGQHK
TNHEDTELHK NGCVMQCLLE KDGLMSGADY DEEKMREDYI KETGAQPGDQ RIEALNACMQ
ETKDMEDKCD KSLLLVACVL AAEAVLADSN EGA
