PBGP9_SOLMG
ID PBGP9_SOLMG Reviewed; 153 AA.
AC Q5EP01; A9LKF2; A9LKF3; A9LKF4; Q5ENZ9;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 41.
DE RecName: Full=Pheromone-binding protein Gp-9;
DE Short=PBP;
DE AltName: Full=Putative odorant-binding protein Gp-9;
DE Flags: Precursor;
GN Name=Gp-9 {ECO:0000312|EMBL:AAW80697.1};
OS Solenopsis megergates (Fire ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Solenopsis.
OX NCBI_TaxID=310439;
RN [1] {ECO:0000305, ECO:0000312|EMBL:AAW80696.1}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELES B1; B2 AND B), AND VARIANTS
RP THR-39; GLY-42; ILE-95; THR-117; ALA-136; ILE-139; LYS-151 AND ALA-152.
RX PubMed=15987877; DOI=10.1093/molbev/msi203;
RA Krieger M.J.B., Ross K.G.;
RT "Molecular evolutionary analyses of the odorant-binding protein gene Gp-9
RT in fire ants and other Solenopsis species.";
RL Mol. Biol. Evol. 22:2090-2103(2005).
RN [2] {ECO:0000305, ECO:0000312|EMBL:ABX25630.1}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 7-153, AND VARIANTS LYS-25; GLU-35;
RP ASP-45; LEU-75; MET-78; THR-105 AND GLU-106.
RC STRAIN=G-77/a {ECO:0000312|EMBL:ABX25630.1},
RC G-77/b {ECO:0000312|EMBL:ABX25631.1}, and
RC G-79 {ECO:0000312|EMBL:ABX25632.1};
RX PubMed=17987107; DOI=10.1371/journal.pone.0001088;
RA Gotzek D., Shoemaker D.D., Ross K.G.;
RT "Molecular variation at a candidate gene implicated in the regulation of
RT fire ant social behavior.";
RL PLoS ONE 2:E1088-E1088(2007).
CC -!- FUNCTION: Colony queen number, a major feature of social organization,
CC is associated with worker genotype for Gp-9. Colonies are headed by
CC either a single reproductive queen (monogyne form) or multiple queens
CC (polygyne form). Differences in worker Gp-9 genotypes between social
CC forms may cause differences in workers' abilities to recognize queens
CC and regulate their numbers (By similarity).
CC {ECO:0000250|UniProtKB:Q8WP90}.
CC -!- SUBUNIT: Homodimer. {ECO:0000250|UniProtKB:P20797}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- POLYMORPHISM: Alleles B1 and B2 are shown, a polygyne population from
CC Brazil. {ECO:0000269|PubMed:15987877}.
CC -!- SIMILARITY: Belongs to the PBP/GOBP family. {ECO:0000255}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY818629; AAW80696.1; -; Genomic_DNA.
DR EMBL; AY818630; AAW80697.1; -; Genomic_DNA.
DR EMBL; AY818631; AAW80698.1; -; Genomic_DNA.
DR EMBL; AY818632; AAW80699.1; -; Genomic_DNA.
DR EMBL; EU220051; ABX25630.1; -; Genomic_DNA.
DR EMBL; EU220052; ABX25631.1; -; Genomic_DNA.
DR EMBL; EU220053; ABX25632.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5EP01; -.
DR SMR; Q5EP01; -.
DR GO; GO:0005615; C:extracellular space; ISS:UniProtKB.
DR GO; GO:0005550; F:pheromone binding; IEA:UniProtKB-KW.
DR GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
DR GO; GO:0035176; P:social behavior; ISS:UniProtKB.
DR Gene3D; 1.10.238.20; -; 1.
DR InterPro; IPR006170; PBP/GOBP.
DR InterPro; IPR036728; PBP_GOBP_sf.
DR InterPro; IPR022354; Pheromone-bd_protein_Gp-9.
DR Pfam; PF01395; PBP_GOBP; 1.
DR PRINTS; PR02007; ODORANTBPGP9.
DR SUPFAM; SSF47565; SSF47565; 1.
PE 3: Inferred from homology;
KW Behavior; Disulfide bond; Pheromone response; Pheromone-binding; Secreted;
KW Signal; Transport.
FT SIGNAL 1..19
FT /evidence="ECO:0000250|UniProtKB:Q8WP90"
FT CHAIN 20..153
FT /note="Pheromone-binding protein Gp-9"
FT /evidence="ECO:0000250|UniProtKB:Q8WP90"
FT /id="PRO_5000094274"
FT DISULFID 37..77
FT /evidence="ECO:0000250|UniProtKB:P20797"
FT DISULFID 73..129
FT /evidence="ECO:0000250|UniProtKB:P20797"
FT DISULFID 118..138
FT /evidence="ECO:0000250|UniProtKB:P20797"
FT VARIANT 25
FT /note="R -> K (in strain: G-77/a, G-77/b and G-79)"
FT /evidence="ECO:0000269|PubMed:17987107"
FT VARIANT 35
FT /note="A -> E (in strain: G-77/a, G-77/b and G-79)"
FT /evidence="ECO:0000269|PubMed:17987107"
FT VARIANT 39
FT /note="A -> T (in allele b)"
FT /evidence="ECO:0000269|PubMed:15987877"
FT VARIANT 42
FT /note="S -> G (in allele b)"
FT /evidence="ECO:0000269|PubMed:15987877"
FT VARIANT 45
FT /note="E -> D (in strain: G-77/a, G-77/b and G-79)"
FT /evidence="ECO:0000269|PubMed:17987107"
FT VARIANT 75
FT /note="M -> L (in strain: G-77/a, G-77/b and G-79)"
FT /evidence="ECO:0000269|PubMed:17987107"
FT VARIANT 78
FT /note="L -> M (in strain: G-77/a, G-77/b and G-79)"
FT /evidence="ECO:0000269|PubMed:17987107"
FT VARIANT 95
FT /note="M -> I (in allele b)"
FT /evidence="ECO:0000269|PubMed:15987877"
FT VARIANT 105
FT /note="A -> T (in strain: G-77/a, G-77/b and G-79)"
FT /evidence="ECO:0000269|PubMed:17987107"
FT VARIANT 106
FT /note="Q -> E (in strain: G-77/a, G-77/b and G-79)"
FT /evidence="ECO:0000269|PubMed:17987107"
FT VARIANT 117
FT /note="A -> T (in allele b)"
FT /evidence="ECO:0000269|PubMed:15987877"
FT VARIANT 136
FT /note="V -> A (in allele b)"
FT /evidence="ECO:0000269|PubMed:15987877"
FT VARIANT 139
FT /note="V -> I (in allele b)"
FT /evidence="ECO:0000269|PubMed:15987877"
FT VARIANT 151
FT /note="E -> K (in allele b)"
FT /evidence="ECO:0000269|PubMed:15987877"
FT VARIANT 152
FT /note="G -> A (in allele b)"
FT /evidence="ECO:0000269|PubMed:15987877"
SQ SEQUENCE 153 AA; 16847 MW; A1439A98AEBE3560 CRC64;
MKTFVLHIFI FALVAFASAS RDSARKIGSQ YDNYATCLAE HSLTEDDIFS IGEVSSGQHK
TNHEDTELHK NGCVMQCLLE KDGLMSGADY DEEKMREDYI KETGAQPGDQ RIEALNACMQ
ETKDMEDKCD KSLLLVACVL AAEAVLADSN EGA
