PBGP9_SOLSV
ID PBGP9_SOLSV Reviewed; 153 AA.
AC Q5ENZ1; A9LKE1; A9LKE2; Q5ENZ5; Q8WRQ3;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 43.
DE RecName: Full=Pheromone-binding protein Gp-9;
DE Short=PBP;
DE AltName: Full=Putative odorant-binding protein Gp-9;
DE Flags: Precursor;
GN Name=Gp-9 {ECO:0000312|EMBL:AAW80707.1};
OS Solenopsis saevissima (Fire ant) (Myrmecia saevissima).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Solenopsis.
OX NCBI_TaxID=176597;
RN [1] {ECO:0000312|EMBL:AAL51118.1}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11711637; DOI=10.1126/science.1065247;
RA Krieger M.J.B., Ross K.G.;
RT "Identification of a major gene regulating complex social behavior.";
RL Science 295:328-332(2002).
RN [2] {ECO:0000305, ECO:0000312|EMBL:AAW80707.1}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELES B2; B3; B4; B5 AND B6).
RX PubMed=15987877; DOI=10.1093/molbev/msi203;
RA Krieger M.J.B., Ross K.G.;
RT "Molecular evolutionary analyses of the odorant-binding protein gene Gp-9
RT in fire ants and other Solenopsis species.";
RL Mol. Biol. Evol. 22:2090-2103(2005).
RN [3] {ECO:0000312|EMBL:ABX25617.1}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=O-3m {ECO:0000312|EMBL:ABX25617.1},
RC W-31 {ECO:0000312|EMBL:ABX25618.1}, W-42 {ECO:0000312|EMBL:ABX25619.1}, and
RC W-72 {ECO:0000312|EMBL:ABX25620.1};
RX PubMed=17987107; DOI=10.1371/journal.pone.0001088;
RA Gotzek D., Shoemaker D.D., Ross K.G.;
RT "Molecular variation at a candidate gene implicated in the regulation of
RT fire ant social behavior.";
RL PLoS ONE 2:E1088-E1088(2007).
CC -!- FUNCTION: Colony queen number, a major feature of social organization,
CC is associated with worker genotype for Gp-9. Colonies are headed by
CC either a single reproductive queen (monogyne form) or multiple queens
CC (polygyne form). Differences in worker Gp-9 genotypes between social
CC forms may cause differences in workers' abilities to recognize queens
CC and regulate their numbers (By similarity).
CC {ECO:0000250|UniProtKB:Q8WP90}.
CC -!- SUBUNIT: Homodimer. {ECO:0000250|UniProtKB:P20797}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- POLYMORPHISM: Allele B2, monogyne population from Brazil.
CC {ECO:0000269|PubMed:15987877}.
CC -!- SIMILARITY: Belongs to the PBP/GOBP family. {ECO:0000255}.
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DR EMBL; AF427892; AAL51118.1; -; Genomic_DNA.
DR EMBL; AY818636; AAW80703.1; -; Genomic_DNA.
DR EMBL; AY818637; AAW80704.1; -; Genomic_DNA.
DR EMBL; AY818638; AAW80705.1; -; Genomic_DNA.
DR EMBL; AY818639; AAW80706.1; -; Genomic_DNA.
DR EMBL; AY818640; AAW80707.1; -; Genomic_DNA.
DR EMBL; EU220038; ABX25617.1; -; Genomic_DNA.
DR EMBL; EU220039; ABX25618.1; -; Genomic_DNA.
DR EMBL; EU220040; ABX25619.1; -; Genomic_DNA.
DR EMBL; EU220041; ABX25620.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5ENZ1; -.
DR SMR; Q5ENZ1; -.
DR GO; GO:0005615; C:extracellular space; ISS:UniProtKB.
DR GO; GO:0005550; F:pheromone binding; IEA:UniProtKB-KW.
DR GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
DR GO; GO:0035176; P:social behavior; ISS:UniProtKB.
DR Gene3D; 1.10.238.20; -; 1.
DR InterPro; IPR006170; PBP/GOBP.
DR InterPro; IPR036728; PBP_GOBP_sf.
DR InterPro; IPR022354; Pheromone-bd_protein_Gp-9.
DR Pfam; PF01395; PBP_GOBP; 1.
DR PRINTS; PR02007; ODORANTBPGP9.
DR SUPFAM; SSF47565; SSF47565; 1.
PE 3: Inferred from homology;
KW Behavior; Disulfide bond; Pheromone response; Pheromone-binding; Secreted;
KW Signal; Transport.
FT SIGNAL 1..19
FT /evidence="ECO:0000250|UniProtKB:Q8WP90"
FT CHAIN 20..153
FT /note="Pheromone-binding protein Gp-9"
FT /evidence="ECO:0000250|UniProtKB:Q8WP90"
FT /id="PRO_5000094284"
FT DISULFID 37..77
FT /evidence="ECO:0000250|UniProtKB:P20797"
FT DISULFID 73..129
FT /evidence="ECO:0000250|UniProtKB:P20797"
FT DISULFID 118..138
FT /evidence="ECO:0000250|UniProtKB:P20797"
FT VARIANT 35
FT /note="E -> A (in allele B6)"
FT /evidence="ECO:0000269|PubMed:15987877"
FT VARIANT 42
FT /note="G -> S (in allele B6)"
FT /evidence="ECO:0000269|PubMed:15987877"
FT VARIANT 45
FT /note="D -> E (in allele B6)"
FT /evidence="ECO:0000269|PubMed:15987877"
FT VARIANT 48
FT /note="V -> I (in allele B6)"
FT /evidence="ECO:0000269|PubMed:15987877"
FT VARIANT 65
FT /note="D -> E (in allele B6)"
FT /evidence="ECO:0000269|PubMed:15987877"
FT VARIANT 75
FT /note="L -> M (in allele B6)"
FT /evidence="ECO:0000269|PubMed:15987877"
FT VARIANT 119
FT /note="M -> I (in allele B3, allele B4 and allele B5)"
FT /evidence="ECO:0000269|PubMed:15987877"
FT VARIANT 123
FT /note="T -> K (in allele B6)"
FT /evidence="ECO:0000269|PubMed:15987877"
SQ SEQUENCE 153 AA; 16831 MW; B4C02A812AA4170D CRC64;
MKTFVLHIFI FALVAFASAS RDSAKKIGSQ YDNYETCLTE HGLTDDDVFS IGEVSSGQHK
TNHEDTELHK NGCVLQCMLE KDGLMSGADY DEEKMREDYI KETGAQPGDQ RIEALNACMH
ETTDMEDKCD KSLLLVACVL AAEAVLADSN EGA
