ID   PBLD_RAT                Reviewed;         288 AA.
AC   Q68G31; Q8R423;
DT   11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Phenazine biosynthesis-like domain-containing protein;
DE            EC=5.1.-.-;
GN   Name=Pbld; Synonyms=Mawbp;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Pawlak A., Guellaen G.;
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBUNIT: Interacts with UNRIP/MAWD. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PhzF family. {ECO:0000305}.
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DR   EMBL; AY083160; AAL92521.1; -; mRNA.
DR   EMBL; BC078735; AAH78735.1; -; mRNA.
DR   RefSeq; NP_612539.2; NM_138530.2.
DR   RefSeq; XP_006256434.1; XM_006256372.3.
DR   RefSeq; XP_017457025.1; XM_017601536.1.
DR   AlphaFoldDB; Q68G31; -.
DR   SMR; Q68G31; -.
DR   STRING; 10116.ENSRNOP00000000434; -.
DR   iPTMnet; Q68G31; -.
DR   PhosphoSitePlus; Q68G31; -.
DR   PaxDb; Q68G31; -.
DR   PRIDE; Q68G31; -.
DR   Ensembl; ENSRNOT00000000434; ENSRNOP00000000434; ENSRNOG00000000386.
DR   GeneID; 171564; -.
DR   KEGG; rno:171564; -.
DR   UCSC; RGD:621263; rat.
DR   CTD; 68371; -.
DR   RGD; 621263; Pbld.
DR   eggNOG; KOG3033; Eukaryota.
DR   GeneTree; ENSGT00390000017595; -.
DR   HOGENOM; CLU_048756_2_0_1; -.
DR   InParanoid; Q68G31; -.
DR   OMA; DWALRWF; -.
DR   OrthoDB; 1361558at2759; -.
DR   PhylomeDB; Q68G31; -.
DR   TreeFam; TF314596; -.
DR   PRO; PR:Q68G31; -.
DR   Proteomes; UP000002494; Chromosome 20.
DR   Bgee; ENSRNOG00000000386; Expressed in adult mammalian kidney and 18 other tissues.
DR   Genevisible; Q68G31; RN.
DR   GO; GO:0005737; C:cytoplasm; ISO:RGD.
DR   GO; GO:0042802; F:identical protein binding; ISO:RGD.
DR   GO; GO:0016853; F:isomerase activity; IBA:GO_Central.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0030277; P:maintenance of gastrointestinal epithelium; ISO:RGD.
DR   GO; GO:0060392; P:negative regulation of SMAD protein signal transduction; ISO:RGD.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; ISO:RGD.
DR   InterPro; IPR003719; Phenazine_PhzF.
DR   PANTHER; PTHR13774; PTHR13774; 1.
DR   Pfam; PF02567; PhzC-PhzF; 1.
DR   PIRSF; PIRSF016184; PhzC_PhzF; 1.
DR   TIGRFAMs; TIGR00654; PhzF_family; 1.
PE   2: Evidence at transcript level;
KW   Isomerase; Reference proteome.
FT   CHAIN           1..288
FT                   /note="Phenazine biosynthesis-like domain-containing
FT                   protein"
FT                   /id="PRO_0000245584"
FT   ACT_SITE        46
FT                   /evidence="ECO:0000250"
FT   CONFLICT        17
FT                   /note="H -> R (in Ref. 1; AAL92521)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        83
FT                   /note="T -> R (in Ref. 1; AAL92521)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        221
FT                   /note="W -> R (in Ref. 1; AAL92521)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        245
FT                   /note="L -> V (in Ref. 1; AAL92521)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   288 AA;  31687 MW;  BD864F97890B7E25 CRC64;
     MKLPIFIADA FTVTAFHGNP AAVCLLESIL QEDAHQQIAR EMNLSETAFI RKLQPTDSFS
     QSSCFGLRWF TPVSEVPLCG HATMASAAVL FHKIKNVNST LTFVTLSGEL KARRAEDGIV
     LDFPLYPTFP QDFHEVKDLI KAAIGDTTVQ DIQYSPDTRK LLVRLSDSYD RSFLESLKVN
     TEPLPGIEKT GKVKGLILTV KGESGGQTTP YDFYSRYFAP WVGVPEDPVT GSAHTVLSSY
     WSQQLGKKEM RAFQCSCRGG ELDISLRPDG RVDMKGGAAV VLEGMLTA