ID   PBP_BRUA2               Reviewed;         350 AA.
AC   Q2YKI6;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Purine-binding protein BAB2_0673;
DE   Flags: Precursor;
GN   OrderedLocusNames=BAB2_0673;
OS   Brucella abortus (strain 2308).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=359391;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2308;
RX   PubMed=16299333; DOI=10.1128/iai.73.12.8353-8361.2005;
RA   Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A.,
RA   Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.;
RT   "Whole-genome analyses of speciation events in pathogenic Brucellae.";
RL   Infect. Immun. 73:8353-8361(2005).
CC   -!- FUNCTION: Binds adenine and probably also other purines, such as
CC       guanine. May play a role in adenine and guanine uptake. May be part of
CC       an ABC-type uptake system for adenine and similar ligands (By
CC       similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BMP lipoprotein family. {ECO:0000305}.
CC   -!- CAUTION: Lacks the conserved Cys that is essential for lipidation.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM040265; CAJ12839.1; -; Genomic_DNA.
DR   PDB; 3S99; X-ray; 2.05 A; A=17-350.
DR   PDBsum; 3S99; -.
DR   AlphaFoldDB; Q2YKI6; -.
DR   SMR; Q2YKI6; -.
DR   STRING; 359391.BAB2_0673; -.
DR   EnsemblBacteria; CAJ12839; CAJ12839; BAB2_0673.
DR   KEGG; bmf:BAB2_0673; -.
DR   PATRIC; fig|359391.11.peg.2857; -.
DR   HOGENOM; CLU_038813_2_0_5; -.
DR   OMA; PYTNMPD; -.
DR   Proteomes; UP000002719; Chromosome II.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   InterPro; IPR003760; PnrA-like.
DR   Pfam; PF02608; Bmp; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..350
FT                   /note="Purine-binding protein BAB2_0673"
FT                   /id="PRO_0000412071"
FT   BINDING         36
FT                   /ligand="adenine"
FT                   /ligand_id="ChEBI:CHEBI:16708"
FT   BINDING         185
FT                   /ligand="adenine"
FT                   /ligand_id="ChEBI:CHEBI:16708"
FT   BINDING         211
FT                   /ligand="adenine"
FT                   /ligand_id="ChEBI:CHEBI:16708"
FT   STRAND          21..26
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   HELIX           31..33
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   HELIX           36..51
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   TURN            52..54
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   STRAND          55..60
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   HELIX           67..78
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   STRAND          82..86
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   HELIX           89..91
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   HELIX           92..99
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   STRAND          105..111
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   STRAND          119..124
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   HELIX           126..140
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   STRAND          145..150
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   HELIX           155..169
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   STRAND          176..181
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   STRAND          183..185
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   HELIX           188..200
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   STRAND          204..213
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   HELIX           214..221
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   STRAND          225..231
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   HELIX           234..236
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   TURN            238..240
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   STRAND          241..247
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   HELIX           250..261
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   STRAND          269..272
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   TURN            274..277
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   STRAND          278..281
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   HELIX           289..303
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   STRAND          309..316
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   STRAND          321..323
FT                   /evidence="ECO:0007829|PDB:3S99"
FT   HELIX           331..335
FT                   /evidence="ECO:0007829|PDB:3S99"
SQ   SEQUENCE   350 AA;  38404 MW;  4ED7EE367362ADC7 CRC64;
     MVIATVAGFM LGGAAHAEEK LKVGFIYIGP PGDFGWTYQH DQARKELVEA LGDKVETTFL
     ENVAEGADAE RSIKRIARAG NKLIFTTSFG YMDPTVKVAK KFPDVKFEHA TGYKTADNMS
     AYNARFYEGR YVQGVIAAKM SKKGIAGYIG SVPVPEVVQG INSFMLGAQS VNPDFRVKVI
     WVNSWFDPGK EADAAKALID QGVDIITQHT DSTAAIQVAH DRGIKAFGQA SDMIKFAPDT
     QLTAVVDEWG PYYIDRAKAV LDGTWKSQNI WWGMKEGLVK MAPFTNMPDD VKKLAEETEA
     RIKSGELNPF TGPIKKQDGS EWLKAGEKAD DQTLLGMNFY VAGVDDKLPQ