ID   PBP_HELVI               Reviewed;         163 AA.
AC   Q27388;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 2.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Pheromone-binding protein;
DE            Short=PBP;
DE   Flags: Precursor;
OS   Heliothis virescens (Tobacco budworm moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC   Noctuidae; Heliothinae; Heliothis.
OX   NCBI_TaxID=7102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Antenna;
RX   PubMed=8508187; DOI=10.1016/0965-1748(93)90052-t;
RA   Krieger J., Ganssle H., Raming K., Breer H.;
RT   "Odorant binding proteins of Heliothis virescens.";
RL   Insect Biochem. Mol. Biol. 23:449-456(1993).
RN   [2]
RP   SEQUENCE REVISION TO 10-15 AND 72.
RC   TISSUE=Antenna;
RA   Krieger J.;
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This major soluble protein in olfactory sensilla of male
CC       moths might serve to solubilize the extremely hydrophobic pheromone
CC       molecules and to transport pheromone through the aqueous lymph to
CC       receptors located on olfactory cilia. {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Antenna.
CC   -!- SIMILARITY: Belongs to the PBP/GOBP family. {ECO:0000305}.
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DR   EMBL; X96861; CAA65604.2; -; mRNA.
DR   PIR; A56584; A56584.
DR   AlphaFoldDB; Q27388; -.
DR   SMR; Q27388; -.
DR   GO; GO:0005550; F:pheromone binding; IEA:UniProtKB-KW.
DR   GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.238.20; -; 1.
DR   InterPro; IPR006072; Odorant/phero-bd_Lep.
DR   InterPro; IPR006170; PBP/GOBP.
DR   InterPro; IPR036728; PBP_GOBP_sf.
DR   Pfam; PF01395; PBP_GOBP; 1.
DR   PIRSF; PIRSF015604; Odorant/phero_bd; 1.
DR   PRINTS; PR00484; PBPGOBP.
DR   SMART; SM00708; PhBP; 1.
DR   SUPFAM; SSF47565; SSF47565; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Pheromone response; Pheromone-binding; Signal; Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..163
FT                   /note="Pheromone-binding protein"
FT                   /id="PRO_0000012562"
FT   DISULFID        39..74
FT                   /evidence="ECO:0000250"
FT   DISULFID        70..129
FT                   /evidence="ECO:0000250"
FT   DISULFID        117..138
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   163 AA;  18356 MW;  8593F851E07F2A83 CRC64;
     MMSVRLMLVV AVWLCLRVDA SQDVMKNLSM NFAKPLEDCK KEMDLPDSVT TDFYNFWKEG
     YEFTNRHTGC AILCLSSKLE LLDQEMKLHH GKAQEFAKKH GADDAMAKQL VDMIHGCSQS
     TPDATDDPCM KALNVAKCFK AKIHELNWAP SMELVVGEVL AEV