PBRP2_ARATH
ID PBRP2_ARATH Reviewed; 336 AA.
AC Q9LIA6; Q6S7A3;
DT 06-JUL-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 147.
DE RecName: Full=Plant-specific TFIIB-related protein 2 {ECO:0000303|PubMed:21390310};
DE Short=AtPBRP2 {ECO:0000303|PubMed:21390310};
DE AltName: Full=TFIIB-related protein PBRP2 {ECO:0000305};
GN Name=PBRP2 {ECO:0000303|PubMed:21390310}; Synonyms=TFIIB3 {ECO:0000305};
GN OrderedLocusNames=At3g29380 {ECO:0000312|Araport:AT3G29380};
GN ORFNames=MUO10.10 {ECO:0000312|EMBL:BAB02583.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RA Lawit S.J., Gurley W.B.;
RT "Binary protein-protein interactions of Arabidopsis thaliana general
RT transcription factors TFIIa, TFIIb, TFIId, TFIIe, and TFIIf.";
RL Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND DISRUPTION
RP PHENOTYPE.
RX PubMed=21390310; DOI=10.1371/journal.pone.0017216;
RA Cavel E., Pillot M., Pontier D., Lahmy S., Bies-Etheve N., Vega D.,
RA Grimanelli D., Lagrange T.;
RT "A plant-specific transcription factor IIB-related protein, pBRP2, is
RT involved in endosperm growth control.";
RL PLoS ONE 6:E17216-E17216(2011).
CC -!- FUNCTION: Plant-specific TFIIB-related protein involved in the
CC regulation of endosperm proliferation during the syncytial phase of
CC endosperm development. Does not contribute to RNA polymerase IV or V
CC activities in reproductive tissues. {ECO:0000269|PubMed:21390310}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:21390310}.
CC -!- TISSUE SPECIFICITY: Specifically expressed in reproductive organs and
CC seeds. {ECO:0000269|PubMed:21390310}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions, but embryos of mutant plants display a reduced rate of
CC endosperm proliferation during the syncytial phase of endosperm
CC development. {ECO:0000269|PubMed:21390310}.
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DR EMBL; AY463629; AAR28031.1; -; mRNA.
DR EMBL; AP001309; BAB02583.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE77578.1; -; Genomic_DNA.
DR RefSeq; NP_189584.1; NM_113864.1.
DR AlphaFoldDB; Q9LIA6; -.
DR SMR; Q9LIA6; -.
DR STRING; 3702.AT3G29380.1; -.
DR iPTMnet; Q9LIA6; -.
DR PaxDb; Q9LIA6; -.
DR PRIDE; Q9LIA6; -.
DR EnsemblPlants; AT3G29380.1; AT3G29380.1; AT3G29380.
DR GeneID; 822598; -.
DR Gramene; AT3G29380.1; AT3G29380.1; AT3G29380.
DR KEGG; ath:AT3G29380; -.
DR Araport; AT3G29380; -.
DR TAIR; locus:2093852; AT3G29380.
DR eggNOG; KOG1597; Eukaryota.
DR HOGENOM; CLU_043736_1_1_1; -.
DR InParanoid; Q9LIA6; -.
DR OMA; REVACVI; -.
DR OrthoDB; 729732at2759; -.
DR PhylomeDB; Q9LIA6; -.
DR PRO; PR:Q9LIA6; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LIA6; baseline and differential.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0097550; C:transcription preinitiation complex; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0017025; F:TBP-class protein binding; IBA:GO_Central.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR GO; GO:0009960; P:endosperm development; IMP:TAIR.
DR GO; GO:0000769; P:syncytium formation by mitosis without cytokinesis; IMP:TAIR.
DR GO; GO:0070897; P:transcription preinitiation complex assembly; IEA:InterPro.
DR CDD; cd00043; CYCLIN; 1.
DR InterPro; IPR013763; Cyclin-like.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR000812; TFIIB.
DR InterPro; IPR013150; TFIIB_cyclin.
DR InterPro; IPR013137; Znf_TFIIB.
DR PANTHER; PTHR11618; PTHR11618; 1.
DR Pfam; PF08271; TF_Zn_Ribbon; 1.
DR Pfam; PF00382; TFIIB; 2.
DR PRINTS; PR00685; TIFACTORIIB.
DR SUPFAM; SSF47954; SSF47954; 2.
DR PROSITE; PS51134; ZF_TFIIB; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..336
FT /note="Plant-specific TFIIB-related protein 2"
FT /id="PRO_0000436815"
FT ZN_FING 2..34
FT /note="TFIIB-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00469"
FT BINDING 6
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00469"
FT BINDING 9
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00469"
FT BINDING 26
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00469"
FT BINDING 29
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00469"
FT CONFLICT 222
FT /note="E -> D (in Ref. 1; AAR28031)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 336 AA; 37719 MW; DDCBEABC26101300 CRC64;
MEEETCLDCK RPTIMVVDHS SGDTICSECG LVLEAHIIEY SQEWRTFASD DNHSDRDPNR
VGAATNPFLK SGDLVTIIEK PKETASSVLS KDDISTLFRA HNQVKNHEED LIKQAFEEIQ
RMTDALDLDI VINSRACEIV SKYDGHANTK LRRGKKLNAI CAASVSTACR ELQLSRTLKE
IAEVANGVDK KDIRKESLVI KRVLESHQTS VSASQAIINT GELVRRFCSK LDISQREIMA
IPEAVEKAEN FDIRRNPKSV LAAIIFMISH ISQTNRKPIR EIGIVAEVVE NTIKNSVKDM
YPYALKIIPN WYACESDIIK RLDGVITSWD SAKFSV
