PCAJ_PSEPU
ID PCAJ_PSEPU Reviewed; 213 AA.
AC P0A102; Q01104;
DT 01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 59.
DE RecName: Full=3-oxoadipate CoA-transferase subunit B;
DE EC=2.8.3.6;
DE AltName: Full=Beta-ketoadipate:succinyl-CoA transferase subunit B;
GN Name=pcaJ;
OS Pseudomonas putida (Arthrobacter siderocapsulatus).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=303;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=PRS2000;
RX PubMed=1624453; DOI=10.1128/jb.174.14.4657-4666.1992;
RA Parales R.E., Harwood C.S.;
RT "Characterization of the genes encoding beta-ketoadipate: succinyl-coenzyme
RT A transferase in Pseudomonas putida.";
RL J. Bacteriol. 174:4657-4666(1992).
RN [2]
RP PROTEIN SEQUENCE OF 2-7.
RX PubMed=6780551; DOI=10.1016/s0021-9258(19)69841-8;
RA Yeh W.-K., Ornston L.N.;
RT "Evolutionarily homologous alpha 2 beta 2 oligomeric structures in beta-
RT ketoadipate succinyl-CoA transferases from Acinetobacter calcoaceticus and
RT Pseudomonas putida.";
RL J. Biol. Chem. 256:1565-1569(1981).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-oxoadipate + succinyl-CoA = 3-oxoadipyl-CoA + succinate;
CC Xref=Rhea:RHEA:12048, ChEBI:CHEBI:15775, ChEBI:CHEBI:30031,
CC ChEBI:CHEBI:57292, ChEBI:CHEBI:57348; EC=2.8.3.6;
CC -!- PATHWAY: Aromatic compound metabolism; beta-ketoadipate pathway;
CC acetyl-CoA and succinyl-CoA from 3-oxoadipate: step 1/2.
CC -!- SUBUNIT: Heterodimer.
CC -!- SIMILARITY: Belongs to the 3-oxoacid CoA-transferase subunit B family.
CC {ECO:0000305}.
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DR EMBL; M88763; AAA25923.1; -; Genomic_DNA.
DR PIR; B42985; B42985.
DR RefSeq; WP_003251131.1; NZ_WOWR01000003.1.
DR AlphaFoldDB; P0A102; -.
DR SMR; P0A102; -.
DR GeneID; 45523298; -.
DR OMA; ANWRVGS; -.
DR BioCyc; MetaCyc:MON-3191; -.
DR BRENDA; 2.8.3.6; 5092.
DR UniPathway; UPA00157; UER00262.
DR GO; GO:0047569; F:3-oxoadipate CoA-transferase activity; IEA:UniProtKB-EC.
DR GO; GO:0042952; P:beta-ketoadipate pathway; IEA:UniProtKB-UniPathway.
DR InterPro; IPR012791; 3-oxoacid_CoA-transf_B.
DR InterPro; IPR004165; CoA_trans_fam_I.
DR InterPro; IPR004164; CoA_transf_AS.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR13707; PTHR13707; 1.
DR Pfam; PF01144; CoA_trans; 1.
DR SMART; SM00882; CoA_trans; 1.
DR SUPFAM; SSF100950; SSF100950; 1.
DR TIGRFAMs; TIGR02428; pcaJ_scoB_fam; 1.
DR PROSITE; PS01274; COA_TRANSF_2; 1.
PE 1: Evidence at protein level;
KW Aromatic hydrocarbons catabolism; Direct protein sequencing; Transferase.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:6780551"
FT CHAIN 2..213
FT /note="3-oxoadipate CoA-transferase subunit B"
FT /id="PRO_0000157919"
FT ACT_SITE 50
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU10034"
SQ SEQUENCE 213 AA; 22552 MW; 5071B33173AD8B7B CRC64;
MTITKKLSRT EMAQRVAADI QEGAYVNLGI GAPTLVANYL GDKEVFLHSE NGLLGMGPSP
APGEEDDDLI NAGKQHVTLL TGGAFFHHAD SFSMMRGGHL DIAVLGAFQV SVKGDLANWH
TGAEGSIPAV GGAMDLATGA RQVFVMMDHL TKTGESKLVP ECTYPLTGIA CVSRIYTDLA
VLEVTPEGLK VVEICADIDF DELQKLSGVP LIK