ASPDH_RAT
ID ASPDH_RAT Reviewed; 297 AA.
AC Q5I0J9;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Aspartate dehydrogenase domain-containing protein {ECO:0000305};
GN Name=Aspdh {ECO:0000312|RGD:1310111};
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Liver;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the L-aspartate dehydrogenase family.
CC {ECO:0000305}.
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DR EMBL; BC088252; AAH88252.1; -; mRNA.
DR RefSeq; NP_001009643.2; NM_001009643.2.
DR AlphaFoldDB; Q5I0J9; -.
DR SMR; Q5I0J9; -.
DR STRING; 10116.ENSRNOP00000063826; -.
DR GeneID; 292875; -.
DR KEGG; rno:292875; -.
DR UCSC; RGD:1310111; rat.
DR CTD; 554235; -.
DR RGD; 1310111; Aspdh.
DR VEuPathDB; HostDB:ENSRNOG00000019424; -.
DR eggNOG; ENOG502QVGC; Eukaryota.
DR InParanoid; Q5I0J9; -.
DR OrthoDB; 1182611at2759; -.
DR PhylomeDB; Q5I0J9; -.
DR TreeFam; TF315092; -.
DR PRO; PR:Q5I0J9; -.
DR Proteomes; UP000002494; Chromosome 1.
DR Bgee; ENSRNOG00000019424; Expressed in liver and 10 other tissues.
DR ExpressionAtlas; Q5I0J9; baseline and differential.
DR Genevisible; Q5I0J9; RN.
DR GO; GO:0033735; F:aspartate dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
DR InterPro; IPR005106; Asp/hSer_DH_NAD-bd.
DR InterPro; IPR002811; Asp_DH.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR Pfam; PF01958; DUF108; 1.
DR Pfam; PF03447; NAD_binding_3; 1.
DR SUPFAM; SSF51735; SSF51735; 1.
PE 2: Evidence at transcript level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..297
FT /note="Aspartate dehydrogenase domain-containing protein"
FT /id="PRO_0000144902"
FT MOD_RES 24
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:A6ND91"
FT MOD_RES 172
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:A6ND91"
SQ SEQUENCE 297 AA; 31260 MW; 572A02B436161734 CRC64;
MDASMVPRVP HKVGVVGYGR LGQSLVSRLL AQGSELGLEL VFVWNRDPGR MAGSVPPALQ
LEDLTTLEER HPDLVVEVAH PKIIHESGVQ ILRHANLLVG SPSALADQTT ERQLLEASNH
WGHTVFVARG ALWGCEDISR LDAAGGLQSL RVTMATHPDG FRLEGPLAAA HSSGPRTVLY
EGPVRGLCPL APRNSNTMAA AALAAPSLGF DRVIGVLVAD LSLTDMHVVD VELTGPQGPQ
AAALPCTPTE RTQPSLALSL APLLLQPSGT AYWAAVSFPP DLGSASAEFP PLPLLSP