ID   ASPDH_XENTR             Reviewed;         284 AA.
AC   Q5FW48;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Aspartate dehydrogenase domain-containing protein;
GN   Name=aspdh;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the L-aspartate dehydrogenase family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC089631; AAH89631.1; -; mRNA.
DR   RefSeq; NP_001015700.1; NM_001015700.1.
DR   AlphaFoldDB; Q5FW48; -.
DR   SMR; Q5FW48; -.
DR   DNASU; 548417; -.
DR   GeneID; 548417; -.
DR   KEGG; xtr:548417; -.
DR   CTD; 554235; -.
DR   Xenbase; XB-GENE-6454901; aspdh.
DR   InParanoid; Q5FW48; -.
DR   Proteomes; UP000008143; Chromosome 7.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0033735; F:aspartate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
DR   InterPro; IPR005106; Asp/hSer_DH_NAD-bd.
DR   InterPro; IPR002811; Asp_DH.
DR   InterPro; IPR011182; L-Asp_DH.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF01958; DUF108; 1.
DR   Pfam; PF03447; NAD_binding_3; 1.
DR   PIRSF; PIRSF005227; Asp_dh_NAD_syn; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..284
FT                   /note="Aspartate dehydrogenase domain-containing protein"
FT                   /id="PRO_0000144904"
SQ   SEQUENCE   284 AA;  31054 MW;  790C024CBE196BCC CRC64;
     MSEERRMRIG VVGYGHIGKY LVDKIVREGA NHSMELAFVW NRRREKLSGA VDPRLQLQDL
     SDCQKWAADL IVEVAHPCIT REYGEKFLSV AHFLVGSPTA LADTVTEAKL RERARLSGNT
     LYVPCGALWG AEDIFKMAER GTLKALRITM TKHPNSFKLE GDLVQKNQEA MSNRTVLYEG
     PVRGLCPLAP NNVNTMAAAC MAAHTLGFDG VVGVLVSDPS VPDWHFVDIE VTGGTIEKTG
     QVFSVKTSRR NPAAPCSVTG SATFASFWSS LLACKGHGGR VYIC