PCD10_HUMAN
ID PCD10_HUMAN Reviewed; 1040 AA.
AC Q9P2E7; Q4W5F6; Q96SF0;
DT 16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT 16-JAN-2004, sequence version 2.
DT 03-AUG-2022, entry version 163.
DE RecName: Full=Protocadherin-10;
DE Flags: Precursor;
GN Name=PCDH10; Synonyms=KIAA1400;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
RX PubMed=11230163; DOI=10.1101/gr.167301;
RA Wu Q., Zhang T., Cheng J.-F., Kim Y., Grimwood J., Schmutz J., Dickson M.,
RA Noonan J.P., Zhang M.Q., Myers R.M., Maniatis T.;
RT "Comparative DNA sequence analysis of mouse and human protocadherin gene
RT clusters.";
RL Genome Res. 11:389-404(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Brain;
RX PubMed=10718198; DOI=10.1093/dnares/7.1.65;
RA Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O.;
RT "Prediction of the coding sequences of unidentified human genes. XVI. The
RT complete sequences of 150 new cDNA clones from brain which code for large
RT proteins in vitro.";
RL DNA Res. 7:65-73(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC TISSUE=Hippocampus;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15815621; DOI=10.1038/nature03466;
RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA Wilson R.K.;
RT "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT 4.";
RL Nature 434:724-731(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE STRUCTURE, AND TISSUE SPECIFICITY.
RX PubMed=11549318; DOI=10.1006/geno.2001.6592;
RA Wolverton T., Lalande M.;
RT "Identification and characterization of three members of a novel subclass
RT of protocadherins.";
RL Genomics 76:66-72(2001).
CC -!- FUNCTION: Potential calcium-dependent cell-adhesion protein.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type I
CC membrane protein {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9P2E7-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9P2E7-2; Sequence=VSP_054404, VSP_054405;
CC -!- TISSUE SPECIFICITY: Moderately expressed in all regions of the brain
CC examined, as well as in testis and ovary, and low expression in all
CC other tissues tested. {ECO:0000269|PubMed:11549318}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA92638.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY013874; AAK21987.1; -; mRNA.
DR EMBL; AB037821; BAA92638.1; ALT_INIT; mRNA.
DR EMBL; AK314377; BAG37004.1; -; mRNA.
DR EMBL; AC105383; AAY41018.1; -; Genomic_DNA.
DR EMBL; CH471056; EAX05151.1; -; Genomic_DNA.
DR EMBL; CH471056; EAX05152.1; -; Genomic_DNA.
DR CCDS; CCDS34063.1; -. [Q9P2E7-1]
DR CCDS; CCDS75192.1; -. [Q9P2E7-2]
DR RefSeq; NP_065866.1; NM_020815.2. [Q9P2E7-2]
DR RefSeq; NP_116586.1; NM_032961.2. [Q9P2E7-1]
DR PDB; 6VFQ; X-ray; 2.30 A; A=18-455.
DR PDB; 6VFW; X-ray; 3.60 A; A/B/C/D/E=18-455.
DR PDB; 6VG4; X-ray; 3.30 A; A=18-680.
DR PDBsum; 6VFQ; -.
DR PDBsum; 6VFW; -.
DR PDBsum; 6VG4; -.
DR AlphaFoldDB; Q9P2E7; -.
DR SMR; Q9P2E7; -.
DR BioGRID; 121628; 59.
DR IntAct; Q9P2E7; 13.
DR STRING; 9606.ENSP00000264360; -.
DR GlyGen; Q9P2E7; 2 sites.
DR iPTMnet; Q9P2E7; -.
DR PhosphoSitePlus; Q9P2E7; -.
DR SwissPalm; Q9P2E7; -.
DR BioMuta; PCDH10; -.
DR DMDM; 41017507; -.
DR jPOST; Q9P2E7; -.
DR MassIVE; Q9P2E7; -.
DR PaxDb; Q9P2E7; -.
DR PeptideAtlas; Q9P2E7; -.
DR PRIDE; Q9P2E7; -.
DR ProteomicsDB; 83796; -. [Q9P2E7-1]
DR Antibodypedia; 2468; 164 antibodies from 26 providers.
DR DNASU; 57575; -.
DR Ensembl; ENST00000264360.7; ENSP00000264360.4; ENSG00000138650.9. [Q9P2E7-1]
DR Ensembl; ENST00000618019.1; ENSP00000480512.1; ENSG00000138650.9. [Q9P2E7-2]
DR GeneID; 57575; -.
DR KEGG; hsa:57575; -.
DR MANE-Select; ENST00000264360.7; ENSP00000264360.4; NM_032961.3; NP_116586.1.
DR UCSC; uc003igz.4; human. [Q9P2E7-1]
DR CTD; 57575; -.
DR DisGeNET; 57575; -.
DR GeneCards; PCDH10; -.
DR HGNC; HGNC:13404; PCDH10.
DR HPA; ENSG00000138650; Tissue enhanced (brain, placenta, seminal vesicle).
DR MIM; 608286; gene.
DR neXtProt; NX_Q9P2E7; -.
DR OpenTargets; ENSG00000138650; -.
DR PharmGKB; PA32995; -.
DR VEuPathDB; HostDB:ENSG00000138650; -.
DR eggNOG; KOG3594; Eukaryota.
DR GeneTree; ENSGT00940000158277; -.
DR HOGENOM; CLU_006480_3_0_1; -.
DR InParanoid; Q9P2E7; -.
DR OMA; FPLEMIV; -.
DR OrthoDB; 64478at2759; -.
DR PhylomeDB; Q9P2E7; -.
DR TreeFam; TF352008; -.
DR PathwayCommons; Q9P2E7; -.
DR SignaLink; Q9P2E7; -.
DR BioGRID-ORCS; 57575; 16 hits in 1075 CRISPR screens.
DR ChiTaRS; PCDH10; human.
DR GeneWiki; PCDH10; -.
DR GenomeRNAi; 57575; -.
DR Pharos; Q9P2E7; Tbio.
DR PRO; PR:Q9P2E7; -.
DR Proteomes; UP000005640; Chromosome 4.
DR RNAct; Q9P2E7; protein.
DR Bgee; ENSG00000138650; Expressed in endothelial cell and 124 other tissues.
DR ExpressionAtlas; Q9P2E7; baseline and differential.
DR Genevisible; Q9P2E7; HS.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IBA:GO_Central.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:Ensembl.
DR GO; GO:0007399; P:nervous system development; IEA:UniProt.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR032455; Cadherin_C.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR InterPro; IPR030712; Protocadherin-10.
DR PANTHER; PTHR24028:SF0; PTHR24028:SF0; 1.
DR Pfam; PF00028; Cadherin; 5.
DR Pfam; PF08266; Cadherin_2; 1.
DR Pfam; PF16492; Cadherin_C_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 6.
DR SUPFAM; SSF49313; SSF49313; 6.
DR PROSITE; PS00232; CADHERIN_1; 5.
DR PROSITE; PS50268; CADHERIN_2; 6.
PE 1: Evidence at protein level;
KW 3D-structure; Alternative splicing; Calcium; Cell adhesion; Cell membrane;
KW Glycoprotein; Membrane; Reference proteome; Repeat; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..1040
FT /note="Protocadherin-10"
FT /id="PRO_0000003995"
FT TOPO_DOM 19..715
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 716..736
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 737..1040
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 19..122
FT /note="Cadherin 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00043"
FT DOMAIN 123..250
FT /note="Cadherin 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00043"
FT DOMAIN 251..358
FT /note="Cadherin 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00043"
FT DOMAIN 359..463
FT /note="Cadherin 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00043"
FT DOMAIN 464..574
FT /note="Cadherin 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00043"
FT DOMAIN 582..690
FT /note="Cadherin 6"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00043"
FT REGION 207..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 686..708
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 899..927
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 908..924
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 273
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 557
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT VAR_SEQ 878..896
FT /note="TKHQRAELSYLVDRPRRVN -> VRLKRKDHHLSSPPSESLL (in
FT isoform 2)"
FT /evidence="ECO:0000303|PubMed:11230163,
FT ECO:0000303|PubMed:14702039"
FT /id="VSP_054404"
FT VAR_SEQ 897..1040
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:11230163,
FT ECO:0000303|PubMed:14702039"
FT /id="VSP_054405"
FT STRAND 20..25
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 33..36
FT /evidence="ECO:0007829|PDB:6VFQ"
FT HELIX 37..41
FT /evidence="ECO:0007829|PDB:6VFQ"
FT HELIX 45..48
FT /evidence="ECO:0007829|PDB:6VFQ"
FT TURN 49..52
FT /evidence="ECO:0007829|PDB:6VFQ"
FT HELIX 57..59
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 64..67
FT /evidence="ECO:0007829|PDB:6VFQ"
FT TURN 68..71
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 72..75
FT /evidence="ECO:0007829|PDB:6VFQ"
FT HELIX 81..85
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 92..99
FT /evidence="ECO:0007829|PDB:6VFQ"
FT TURN 100..103
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 104..113
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 123..132
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 140..142
FT /evidence="ECO:0007829|PDB:6VFQ"
FT HELIX 152..154
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 155..161
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 165..175
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 178..185
FT /evidence="ECO:0007829|PDB:6VFQ"
FT TURN 191..193
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 195..206
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 231..241
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 249..251
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 253..260
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 268..271
FT /evidence="ECO:0007829|PDB:6VFQ"
FT HELIX 280..283
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 285..289
FT /evidence="ECO:0007829|PDB:6VFQ"
FT HELIX 295..300
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 301..303
FT /evidence="ECO:0007829|PDB:6VFQ"
FT TURN 305..307
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 309..312
FT /evidence="ECO:0007829|PDB:6VFQ"
FT TURN 318..320
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 322..334
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 340..349
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 357..363
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 365..367
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 376..383
FT /evidence="ECO:0007829|PDB:6VFQ"
FT HELIX 388..391
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 393..397
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 402..409
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 412..417
FT /evidence="ECO:0007829|PDB:6VFQ"
FT TURN 423..426
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 428..437
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 439..441
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 444..453
FT /evidence="ECO:0007829|PDB:6VFQ"
FT STRAND 462..464
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 466..473
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 480..484
FT /evidence="ECO:0007829|PDB:6VG4"
FT HELIX 493..496
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 498..502
FT /evidence="ECO:0007829|PDB:6VG4"
FT HELIX 512..514
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 516..518
FT /evidence="ECO:0007829|PDB:6VG4"
FT TURN 520..522
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 524..527
FT /evidence="ECO:0007829|PDB:6VG4"
FT TURN 533..535
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 538..547
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 550..552
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 555..565
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 573..577
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 581..583
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 586..590
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 599..602
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 604..606
FT /evidence="ECO:0007829|PDB:6VG4"
FT HELIX 611..613
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 617..620
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 625..627
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 629..631
FT /evidence="ECO:0007829|PDB:6VG4"
FT TURN 633..635
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 637..642
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 654..661
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 664..666
FT /evidence="ECO:0007829|PDB:6VG4"
FT STRAND 669..678
FT /evidence="ECO:0007829|PDB:6VG4"
SQ SEQUENCE 1040 AA; 112936 MW; DE53F8B1A7198F85 CRC64;
MIVLLLFALL WMVEGVFSQL HYTVQEEQEH GTFVGNIAED LGLDITKLSA RGFQTVPNSR
TPYLDLNLET GVLYVNEKID REQICKQSPS CVLHLEVFLE NPLELFQVEI EVLDINDNPP
SFPEPDLTVE ISESATPGTR FPLESAFDPD VGTNSLRDYE ITPNSYFSLD VQTQGDGNRF
AELVLEKPLD REQQAVHRYV LTAVDGGGGG GVGEGGGGGG GAGLPPQQQR TGTALLTIRV
LDSNDNVPAF DQPVYTVSLP ENSPPGTLVI QLNATDPDEG QNGEVVYSFS SHISPRAREL
FGLSPRTGRL EVSGELDYEE SPVYQVYVQA KDLGPNAVPA HCKVLVRVLD ANDNAPEISF
STVKEAVSEG AAPGTVVALF SVTDRDSEEN GQVQCELLGD VPFRLKSSFK NYYTIVTEAP
LDREAGDSYT LTVVARDRGE PALSTSKSIQ VQVSDVNDNA PRFSQPVYDV YVTENNVPGA
YIYAVSATDR DEGANAQLAY SILECQIQGM SVFTYVSINS ENGYLYALRS FDYEQLKDFS
FQVEARDAGS PQALAGNATV NILIVDQNDN APAIVAPLPG RNGTPAREVL PRSAEPGYLL
TRVAAVDADD GENARLTYSI VRGNEMNLFR MDWRTGELRT ARRVPAKRDP QRPYELVIEV
RDHGQPPLSS TATLVVQLVD GAVEPQGGGG SGGGGSGEHQ RPSRSGGGET SLDLTLILII
ALGSVSFIFL LAMIVLAVRC QKEKKLNIYT CLASDCCLCC CCCGGGGSTC CGRQARARKK
KLSKSDIMLV QSSNVPSNPA QVPIEESGGF GSHHHNQNYC YQVCLTPESA KTDLMFLKPC
SPSRSTDTEH NPCGAIVTGY TDQQPDIISN GSILSNETKH QRAELSYLVD RPRRVNSSAF
QEADIVSSKD SGHGDSEQGD SDHDATNRAQ SAGMDLFSNC TEECKALGHS DRCWMPSFVP
SDGRQAADYR SNLHVPGMDS VPDTEVFETP EAQPGAERSF STFGKEKALH STLERKELDG
LLTNTRAPYK PPYLTRKRIC
