PCF1_ORYSJ
ID PCF1_ORYSJ Reviewed; 183 AA.
AC O23875; Q0JEW1; Q7X7G4; Q7XML4;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Transcription factor PCF1 {ECO:0000305};
DE AltName: Full=Proliferating cell factor 1 {ECO:0000303|PubMed:9338963};
GN Name=PCF1 {ECO:0000303|PubMed:9338963};
GN OrderedLocusNames=Os04g0194600, LOC_Os04g11830;
GN ORFNames=OSJNBa0040D17.14, OSJNBb0026E15.1;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, HOMODIMER, AND
RP INTERACTION WITH PCF2.
RC STRAIN=cv. Nipponbare; TISSUE=Meristem;
RX PubMed=9338963; DOI=10.2307/3870447;
RA Kosugi S., Ohashi Y.;
RT "PCF1 and PCF2 specifically bind to cis elements in the rice proliferating
RT cell nuclear antigen gene.";
RL Plant Cell 9:1607-1619(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP FUNCTION.
RX PubMed=12000681; DOI=10.1046/j.1365-313x.2002.01294.x;
RA Kosugi S., Ohashi Y.;
RT "DNA binding and dimerization specificity and potential targets for the TCP
RT protein family.";
RL Plant J. 30:337-348(2002).
RN [7]
RP FUNCTION, INTERACTION WITH SPL14, AND SUBCELLULAR LOCATION.
RX PubMed=24170127; DOI=10.1105/tpc.113.113639;
RA Lu Z., Yu H., Xiong G., Wang J., Jiao Y., Liu G., Jing Y., Meng X., Hu X.,
RA Qian Q., Fu X., Wang Y., Li J.;
RT "Genome-wide binding analysis of the transcription activator ideal plant
RT architecture1 reveals a complex network regulating rice plant
RT architecture.";
RL Plant Cell 25:3743-3759(2013).
CC -!- FUNCTION: Transcription activator. Binds the promoter core sequence 5'-
CC GGNCC-3', especially at sites IIa (5'-GGGCCCAC-3') and IIb (5'-
CC GGTCCCAC-3') (essential for meristematic tissue-specificity expression)
CC of the PCNA gene promoter (PubMed:12000681, PubMed:9338963). Can target
CC the TCP motif 5'-TGGGCC/T-3' (PubMed:24170127).
CC {ECO:0000269|PubMed:12000681, ECO:0000269|PubMed:24170127,
CC ECO:0000269|PubMed:9338963}.
CC -!- SUBUNIT: Forms homodimers and heterodimers with PCF2 (PubMed:9338963).
CC Interacts with SPL14/IPA1 (PubMed:24170127).
CC {ECO:0000269|PubMed:24170127, ECO:0000269|PubMed:9338963}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:24170127}.
CC -!- TISSUE SPECIFICITY: Expressed in seedlings and leaves, mostly in the
CC lower region rich in dividing cells. {ECO:0000269|PubMed:9338963}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF14126.2; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; D87260; BAA23142.1; -; mRNA.
DR EMBL; AL607008; CAE03683.1; -; Genomic_DNA.
DR EMBL; AL662965; CAE04545.2; -; Genomic_DNA.
DR EMBL; AP008210; BAF14126.2; ALT_INIT; Genomic_DNA.
DR EMBL; AP014960; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; T02974; T02974.
DR AlphaFoldDB; O23875; -.
DR STRING; 4530.OS04T0194600-01; -.
DR PaxDb; O23875; -.
DR PRIDE; O23875; -.
DR eggNOG; ENOG502RZSX; Eukaryota.
DR HOGENOM; CLU_1423430_0_0_1; -.
DR InParanoid; O23875; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR Genevisible; O23875; OS.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR InterPro; IPR017887; TF_TCP_subgr.
DR InterPro; IPR005333; Transcription_factor_TCP.
DR PANTHER; PTHR31072; PTHR31072; 1.
DR Pfam; PF03634; TCP; 1.
DR PROSITE; PS51369; TCP; 1.
PE 1: Evidence at protein level;
KW Activator; Developmental protein; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..183
FT /note="Transcription factor PCF1"
FT /id="PRO_0000330803"
FT DOMAIN 56..110
FT /note="TCP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00701"
FT REGION 18..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 157..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..63
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 4
FT /note="S -> SS (in Ref. 3; BAF14126)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 183 AA; 18818 MW; 853A71A230475A98 CRC64;
MMASSDLILY NLVPAQPLNP SAIPNPNPDL SIAAAEPPSS DGATPRRVRP RKSPSSSDRH
SKVAGRGRRV RIPAMVAARV FQLTRELGHR TDGETIEWLL RQAEPSIIAA TGTGVTPEEA
PPAAVAIGSS SVAAAAAAGG HGGAFVHVPY YTALLMQPPN ADEPPMASAA SASGTTAADE
NNN
