PCF2_ORYSJ
ID PCF2_ORYSJ Reviewed; 373 AA.
AC Q6ZBH6; B7E537; O23876;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Transcription factor PCF2 {ECO:0000305};
DE AltName: Full=Proliferating cell factor 2 {ECO:0000303|PubMed:9338963};
GN Name=PCF2 {ECO:0000303|PubMed:9338963};
GN OrderedLocusNames=Os08g0544800, LOC_Os08g43160;
GN ORFNames=OsJ_027020, P0623F08.31;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, HOMODIMER, AND
RP INTERACTION WITH PCF1.
RC STRAIN=cv. Nipponbare; TISSUE=Meristem;
RX PubMed=9338963; DOI=10.2307/3870447;
RA Kosugi S., Ohashi Y.;
RT "PCF1 and PCF2 specifically bind to cis elements in the rice proliferating
RT cell nuclear antigen gene.";
RL Plant Cell 9:1607-1619(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP FUNCTION.
RX PubMed=12000681; DOI=10.1046/j.1365-313x.2002.01294.x;
RA Kosugi S., Ohashi Y.;
RT "DNA binding and dimerization specificity and potential targets for the TCP
RT protein family.";
RL Plant J. 30:337-348(2002).
RN [8]
RP FUNCTION, INTERACTION WITH SPL14, AND SUBCELLULAR LOCATION.
RX PubMed=24170127; DOI=10.1105/tpc.113.113639;
RA Lu Z., Yu H., Xiong G., Wang J., Jiao Y., Liu G., Jing Y., Meng X., Hu X.,
RA Qian Q., Fu X., Wang Y., Li J.;
RT "Genome-wide binding analysis of the transcription activator ideal plant
RT architecture1 reveals a complex network regulating rice plant
RT architecture.";
RL Plant Cell 25:3743-3759(2013).
CC -!- FUNCTION: Transcription activator. Binds the promoter core sequence 5'-
CC GGNCC-3', especially at sites IIa (5'-GGGCCCAC-3') and IIb (5'-
CC GGTCCCAC-3') (essential for meristematic tissue-specificity expression)
CC of the PCNA gene promoter (PubMed:12000681, PubMed:9338963). Can target
CC the TCP motif 5'-TGGGCC/T-3' (PubMed:24170127).
CC {ECO:0000269|PubMed:12000681, ECO:0000269|PubMed:24170127,
CC ECO:0000269|PubMed:9338963}.
CC -!- SUBUNIT: Forms homodimers and heterodimers with PCF1 (PubMed:9338963).
CC Interacts with SPL14/IPA1 (PubMed:24170127).
CC {ECO:0000269|PubMed:24170127, ECO:0000269|PubMed:9338963}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:24170127}.
CC -!- TISSUE SPECIFICITY: Expressed in seedlings and leaves, mostly in the
CC lower region rich in dividing cells. {ECO:0000269|PubMed:9338963}.
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DR EMBL; D87261; BAA23143.1; -; mRNA.
DR EMBL; AP004632; BAD09732.1; -; Genomic_DNA.
DR EMBL; AP008214; BAF24323.1; -; Genomic_DNA.
DR EMBL; AP014964; BAT06528.1; -; Genomic_DNA.
DR EMBL; CM000145; EAZ43537.1; -; Genomic_DNA.
DR EMBL; AK060536; BAG87484.1; -; mRNA.
DR EMBL; AK119660; BAG99734.1; -; mRNA.
DR PIR; T02976; T02976.
DR RefSeq; XP_015648330.1; XM_015792844.1.
DR AlphaFoldDB; Q6ZBH6; -.
DR STRING; 4530.OS08T0544800-01; -.
DR PaxDb; Q6ZBH6; -.
DR PRIDE; Q6ZBH6; -.
DR EnsemblPlants; Os08t0544800-01; Os08t0544800-01; Os08g0544800.
DR GeneID; 4346214; -.
DR Gramene; Os08t0544800-01; Os08t0544800-01; Os08g0544800.
DR KEGG; osa:4346214; -.
DR eggNOG; ENOG502QR5H; Eukaryota.
DR HOGENOM; CLU_050452_0_0_1; -.
DR InParanoid; Q6ZBH6; -.
DR OMA; EGQDRPP; -.
DR OrthoDB; 1456249at2759; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000007752; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR Genevisible; Q6ZBH6; OS.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0001216; F:DNA-binding transcription activator activity; IDA:UniProtKB.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR InterPro; IPR017887; TF_TCP_subgr.
DR InterPro; IPR005333; Transcription_factor_TCP.
DR PANTHER; PTHR31072; PTHR31072; 1.
DR Pfam; PF03634; TCP; 1.
DR PROSITE; PS51369; TCP; 1.
PE 1: Evidence at protein level;
KW Activator; Developmental protein; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..373
FT /note="Transcription factor PCF2"
FT /id="PRO_0000330804"
FT DOMAIN 75..129
FT /note="TCP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00701"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 149..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..352
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..373
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 264
FT /note="Q -> R (in Ref. 1; BAA23143)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 373 AA; 38501 MW; 8A71BFE320AC7B12 CRC64;
MEAQAQDKAE EGEEEGTRQQ HAQAGPVGAA GGGGGGGAAA VAMSAIPMNS WLVPKPEPVE
FFGGMAMVRK PPPRNRDRHT KVEGRGRRIR MPAACAARIF QLTRELGHKS DGETIRWLLQ
QSEPAIIAAT GTGTVPAIAT TVDGVLRIPT QSSSSSGPAS SAVVDGEESS AKRRRKLQPT
RAVAGASPLA TAAPAAYYPV IADPLLQGSG GAAISVPSGL APITATGAPQ GLVPVFAVPA
TGSPAVAGGN RMIPQATAVW MVPQPAGAAG AGNQPTQFWA IQSAPQLVNF AGAQFPTAIN
VADFQQQQQQ QPVSTTIVQN SNSGEHMHFS GADSHEQQRR GRKEGNSGGV VDHPEEDEDD
DDDEPVSDSS PEE
