ID   PCF_BACSU               Reviewed;         169 AA.
AC   P39784;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Positive control factor;
GN   Name=xpf; Synonyms=pcf, ykxE; OrderedLocusNames=BSU12560;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / SO113;
RX   PubMed=8083174; DOI=10.1128/jb.176.18.5820-5830.1994;
RA   McDonnell G.E., Wood H., Devine K.M., McConnell D.J.;
RT   "Genetic control of bacterial suicide: regulation of the induction of PBSX
RT   in Bacillus subtilis.";
RL   J. Bacteriol. 176:5820-5830(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Krogh S., O'Reilly M., Nolan N., Devine K.M.;
RL   Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: Positive regulatory protein that acts at the late promoter
CC       PL.
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DR   EMBL; Z34287; CAA84046.1; -; Genomic_DNA.
DR   EMBL; Z70177; CAA94057.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB13113.1; -; Genomic_DNA.
DR   PIR; I40413; I40413.
DR   RefSeq; NP_389138.1; NC_000964.3.
DR   RefSeq; WP_003245797.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; P39784; -.
DR   SMR; P39784; -.
DR   STRING; 224308.BSU12560; -.
DR   PaxDb; P39784; -.
DR   PRIDE; P39784; -.
DR   EnsemblBacteria; CAB13113; CAB13113; BSU_12560.
DR   GeneID; 936474; -.
DR   KEGG; bsu:BSU12560; -.
DR   PATRIC; fig|224308.179.peg.1360; -.
DR   eggNOG; COG1595; Bacteria.
DR   OMA; CFSYERI; -.
DR   BioCyc; BSUB:BSU12560-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF08281; Sigma70_r4_2; 1.
DR   SUPFAM; SSF88659; SSF88659; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
PE   4: Predicted;
KW   Activator; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..169
FT                   /note="Positive control factor"
FT                   /id="PRO_0000058248"
FT   DNA_BIND        132..157
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   169 AA;  20091 MW;  28E788CFA3375229 CRC64;
     MQDLLFEYKR TLKQTRIQYK PLAEADESVL SAEELKDKKI IRNMITDLEY VTEWLEKGRQ
     PGIRRAIDRR DVYQRLMIKD PRIIESFSSA MMFEPDGQVS EEDRDRIREA LALLTDREKE
     MFLLHKVECF SYERIADLLG VKKSTVQTTI KRASLKMQRQ QEEMNRSLA