PCH2_ORYSI
ID PCH2_ORYSI Reviewed; 471 AA.
AC A2XUN8; Q01JZ0;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 2.
DT 03-AUG-2022, entry version 73.
DE RecName: Full=Pachytene checkpoint protein 2 homolog;
GN ORFNames=OsI_16324, OSIGBa0116M22.9;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Guang-Lu-Ai No.4;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Plays a key role in chromosome recombination during meiosis.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the AAA ATPase family. PCH2 subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAH66942.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=EAY94548.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; CR855156; CAH66942.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CM000129; EAY94548.1; ALT_SEQ; Genomic_DNA.
DR AlphaFoldDB; A2XUN8; -.
DR SMR; A2XUN8; -.
DR STRING; 39946.A2XUN8; -.
DR HOGENOM; CLU_028208_0_1_1; -.
DR Proteomes; UP000007015; Chromosome 4.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR044539; Pch2-like.
DR PANTHER; PTHR45991; PTHR45991; 1.
DR Pfam; PF00004; AAA; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding; Meiosis; Nucleotide-binding; Reference proteome.
FT CHAIN 1..471
FT /note="Pachytene checkpoint protein 2 homolog"
FT /id="PRO_0000410927"
FT BINDING 213..220
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
FT CONFLICT 15
FT /note="S -> SA (in Ref. 1; CAH66942)"
FT /evidence="ECO:0000305"
FT CONFLICT 28..32
FT /note="SAAAV -> AATAA (in Ref. 1; CAH66942)"
FT /evidence="ECO:0000305"
FT CONFLICT 105
FT /note="N -> S (in Ref. 1; CAH66942)"
FT /evidence="ECO:0000305"
FT CONFLICT 118
FT /note="T -> I (in Ref. 1; CAH66942)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 471 AA; 51121 MW; BEEEE5C12C57FAB4 CRC64;
MEVSFSAPPP PDAASAAAAA PSLVPAVSAA AVAATTVSCS PQPPTGSPSA DDRILVSVEV
LLHATSTARA EDVCAAVERM LEARSLSYVD GPVPIPNDDP FLLANVKRIQ ICDTDEWTEN
HKVLLFWQVR PVVHVFQLSE DGPGEEPGED DTLSSFNEWA LPAKEFDGLW ESLLYEVGLK
QRLLRYAASA LLFTEKGVDP CLVSWNRIVL LHGPPGTGKT SLCKALAQKL SIRFKSRYSM
CQLIEVNAHS LFSKWFSESG KLVAKLFQKI QEMVEEESNL VFVLIDEVES LAAARQAAIS
GSEPSDSIRV VNALLTQMDK LKSWPNVIIL TTSNITTAID IAFVDRADIK AYVGPPTLQA
RYEILRSCLQ ELLRVGILTH TQGGNSLCLL SYFSLMENQH CPEVADPHGS VHLSGLLHKA
AEICEGLSGR TLRKLPFLAH ASVANPSCCD ASAFLHALIQ TAQRELSESR G