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PCH2_ORYSI
ID   PCH2_ORYSI              Reviewed;         471 AA.
AC   A2XUN8; Q01JZ0;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 2.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Pachytene checkpoint protein 2 homolog;
GN   ORFNames=OsI_16324, OSIGBa0116M22.9;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Guang-Lu-Ai No.4;
RX   PubMed=12447439; DOI=10.1038/nature01183;
RA   Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA   Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA   Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA   Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA   Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA   Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA   Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA   Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA   Li J., Hong G., Xue Y., Han B.;
RT   "Sequence and analysis of rice chromosome 4.";
RL   Nature 420:316-320(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Plays a key role in chromosome recombination during meiosis.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AAA ATPase family. PCH2 subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAH66942.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=EAY94548.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; CR855156; CAH66942.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CM000129; EAY94548.1; ALT_SEQ; Genomic_DNA.
DR   AlphaFoldDB; A2XUN8; -.
DR   SMR; A2XUN8; -.
DR   STRING; 39946.A2XUN8; -.
DR   HOGENOM; CLU_028208_0_1_1; -.
DR   Proteomes; UP000007015; Chromosome 4.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR003960; ATPase_AAA_CS.
DR   InterPro; IPR001270; ClpA/B.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR044539; Pch2-like.
DR   PANTHER; PTHR45991; PTHR45991; 1.
DR   Pfam; PF00004; AAA; 1.
DR   PRINTS; PR00300; CLPPROTEASEA.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00674; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Meiosis; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..471
FT                   /note="Pachytene checkpoint protein 2 homolog"
FT                   /id="PRO_0000410927"
FT   BINDING         213..220
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        15
FT                   /note="S -> SA (in Ref. 1; CAH66942)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        28..32
FT                   /note="SAAAV -> AATAA (in Ref. 1; CAH66942)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        105
FT                   /note="N -> S (in Ref. 1; CAH66942)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        118
FT                   /note="T -> I (in Ref. 1; CAH66942)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   471 AA;  51121 MW;  BEEEE5C12C57FAB4 CRC64;
     MEVSFSAPPP PDAASAAAAA PSLVPAVSAA AVAATTVSCS PQPPTGSPSA DDRILVSVEV
     LLHATSTARA EDVCAAVERM LEARSLSYVD GPVPIPNDDP FLLANVKRIQ ICDTDEWTEN
     HKVLLFWQVR PVVHVFQLSE DGPGEEPGED DTLSSFNEWA LPAKEFDGLW ESLLYEVGLK
     QRLLRYAASA LLFTEKGVDP CLVSWNRIVL LHGPPGTGKT SLCKALAQKL SIRFKSRYSM
     CQLIEVNAHS LFSKWFSESG KLVAKLFQKI QEMVEEESNL VFVLIDEVES LAAARQAAIS
     GSEPSDSIRV VNALLTQMDK LKSWPNVIIL TTSNITTAID IAFVDRADIK AYVGPPTLQA
     RYEILRSCLQ ELLRVGILTH TQGGNSLCLL SYFSLMENQH CPEVADPHGS VHLSGLLHKA
     AEICEGLSGR TLRKLPFLAH ASVANPSCCD ASAFLHALIQ TAQRELSESR G
 
 
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