PCID2_DICDI
ID PCID2_DICDI Reviewed; 430 AA.
AC Q54PX7;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=PCI domain-containing protein 2 homolog;
DE AltName: Full=CSN12-like protein;
GN Name=pcid2; ORFNames=DDB_G0284241;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SIMILARITY: Belongs to the CSN12 family. {ECO:0000305}.
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DR EMBL; AAFI02000064; EAL65309.1; -; Genomic_DNA.
DR RefSeq; XP_638668.1; XM_633576.1.
DR AlphaFoldDB; Q54PX7; -.
DR SMR; Q54PX7; -.
DR STRING; 44689.DDB0305019; -.
DR PaxDb; Q54PX7; -.
DR PRIDE; Q54PX7; -.
DR EnsemblProtists; EAL65309; EAL65309; DDB_G0284241.
DR GeneID; 8624497; -.
DR KEGG; ddi:DDB_G0284241; -.
DR dictyBase; DDB_G0284241; -.
DR eggNOG; KOG2688; Eukaryota.
DR HOGENOM; CLU_031567_2_0_1; -.
DR InParanoid; Q54PX7; -.
DR OMA; TYLIPCH; -.
DR PhylomeDB; Q54PX7; -.
DR PRO; PR:Q54PX7; -.
DR Proteomes; UP000002195; Chromosome 4.
DR GO; GO:0070390; C:transcription export complex 2; IBA:GO_Central.
DR GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IBA:GO_Central.
DR GO; GO:0000973; P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery; IBA:GO_Central.
DR GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IBA:GO_Central.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR045114; Csn12-like.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR12732; PTHR12732; 1.
DR Pfam; PF01399; PCI; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..430
FT /note="PCI domain-containing protein 2 homolog"
FT /id="PRO_0000328116"
FT DOMAIN 243..424
FT /note="PCI"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01185"
SQ SEQUENCE 430 AA; 49476 MW; B40C7FE8C9988970 CRC64;
MAELTNHFNK VNELLNDWDG VGLSHELSMT ELITSILNSI NHNSHSGMSN QKKQQIQAKV
NQIKKTDLVV KRQQDIDTLC ANKIQHNYNE IVAYRLRSIS SLLDSKYYDA FRYLIEAINS
FVKVFELWSQ NILWRLSLDL RLMAELATLN VGSNDSNNSN NNVTIDYFEE ASRTLLSKCF
QAANADRTPN LAESKKNAAL GVVNQLFQIY FKINNLKLCK NLIKTMESPG FPTLESYPLN
QVITYRFFNG RLSVFNGQYK KAQEELLYAF NKCPNDSIKN KRLILLFLVP MQLEQCKFPK
KSLLEKFKLT QFIDIVQSIK SGNIKQFNEC LSTHQNFFIS KGIYLILEKL KIIVYRNLFK
KVHLITTGQR IPIGNFVSAL KWMENDAIDI DETECILSNL IYNGYLKGYI SHKVALVVSP
TNPFPKLPLN