ID   PCKA_CANGA              Reviewed;         544 AA.
AC   Q6FRR0;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Phosphoenolpyruvate carboxykinase (ATP);
DE            EC=4.1.1.49;
GN   Name=PCK1; OrderedLocusNames=CAGL0H06633g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate;
CC         Xref=Rhea:RHEA:18617, ChEBI:CHEBI:16452, ChEBI:CHEBI:16526,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58702, ChEBI:CHEBI:456216;
CC         EC=4.1.1.49;
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC   -!- SIMILARITY: Belongs to the phosphoenolpyruvate carboxykinase (ATP)
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR380954; CAG60017.1; -; Genomic_DNA.
DR   RefSeq; XP_447084.1; XM_447084.1.
DR   AlphaFoldDB; Q6FRR0; -.
DR   SMR; Q6FRR0; -.
DR   STRING; 5478.XP_447084.1; -.
DR   EnsemblFungi; CAG60017; CAG60017; CAGL0H06633g.
DR   GeneID; 2888554; -.
DR   KEGG; cgr:CAGL0H06633g; -.
DR   CGD; CAL0129906; PCK1.
DR   VEuPathDB; FungiDB:CAGL0H06633g; -.
DR   eggNOG; ENOG502QQI5; Eukaryota.
DR   HOGENOM; CLU_018247_0_1_1; -.
DR   InParanoid; Q6FRR0; -.
DR   OMA; MRYAGEM; -.
DR   UniPathway; UPA00138; -.
DR   Proteomes; UP000002428; Chromosome H.
DR   GO; GO:0009986; C:cell surface; IDA:CGD.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004612; F:phosphoenolpyruvate carboxykinase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR   CDD; cd00484; PEPCK_ATP; 1.
DR   Gene3D; 3.40.449.10; -; 1.
DR   Gene3D; 3.90.228.20; -; 1.
DR   HAMAP; MF_00453; PEPCK_ATP; 1.
DR   InterPro; IPR001272; PEP_carboxykinase_ATP.
DR   InterPro; IPR013035; PEP_carboxykinase_C.
DR   InterPro; IPR008210; PEP_carboxykinase_N.
DR   InterPro; IPR015994; PEPCK_ATP_CS.
DR   PANTHER; PTHR30031; PTHR30031; 1.
DR   Pfam; PF01293; PEPCK_ATP; 1.
DR   PIRSF; PIRSF006294; PEP_crbxkin; 1.
DR   SUPFAM; SSF68923; SSF68923; 1.
DR   TIGRFAMs; TIGR00224; pckA; 1.
DR   PROSITE; PS00532; PEPCK_ATP; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Decarboxylase; Gluconeogenesis; Lyase; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..544
FT                   /note="Phosphoenolpyruvate carboxykinase (ATP)"
FT                   /id="PRO_0000203871"
FT   BINDING         246..253
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   544 AA;  60354 MW;  63901722C8025892 CRC64;
     MPSKSSVSGN SVEERIRSEL GLSKEVTLIR RNAPAAVLYQ DALKEKKTVI SSAGALIAYS
     GEKTGRSPKD KRIVEEETSR DNVWWGPVNK PCSERTWAIN RERAADYLRT RETLYVVDAF
     AGWDPKYRIK VRVVCARAYH ALFMTNMLIR PTEEELANFG EPDFTVWNAG QFPANARTQD
     MTSKTTIEIN FKAMEMVILG TEYAGEMKKG IFTVMFYLMP VHHNVLTLHS SCNQGIKNGD
     VTLFFGLSGT GKTTLSADPH RLLIGDDEHC WSDEGVFNIE GGCYAKCINL SREKEPEIFD
     AIRFGSVLEN VIYDSESHEV DYDDSSITEN TRCAYPIDFI PSAKIPCLAP AHPKNIILLT
     CDASGVLPPV SKLTPEQVMY HFISGYTSKM AGTEQGVTEP EPTFSSCFGQ PFLSLHPMRY
     ATMLAEKMHE HSANAWLINT GWTGSSYVSG GKRCALKYTR AILDAIHDGS LAKAEFESLP
     IFNLQVPKAV EGVPSELLNP ARNWSEGEAK YQSAVSKLAG LFVENFKTYQ DKATSDVLAA
     GPQL