ID   ASPG2_DROSI             Reviewed;         397 AA.
AC   B4QGM0;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 46.
DE   RecName: Full=L-asparaginase-like protein GD25160;
DE   Flags: Precursor;
GN   ORFNames=GD25160;
OS   Drosophila simulans (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7240;
RN   [1] {ECO:0000312|EMBL:EDX08139.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the Ntn-hydrolase family. {ECO:0000255}.
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DR   EMBL; CM000362; EDX08139.1; -; Genomic_DNA.
DR   RefSeq; XP_002082554.1; XM_002082518.2.
DR   AlphaFoldDB; B4QGM0; -.
DR   SMR; B4QGM0; -.
DR   STRING; 7240.B4QGM0; -.
DR   MEROPS; T02.A04; -.
DR   EnsemblMetazoa; FBtr0225070; FBpp0223562; FBgn0196472.
DR   GeneID; 6735634; -.
DR   HOGENOM; CLU_021603_0_0_1; -.
DR   OMA; QAVIQGC; -.
DR   PhylomeDB; B4QGM0; -.
DR   Proteomes; UP000000304; Chromosome 2r.
DR   Bgee; FBgn0196472; Expressed in female reproductive system.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR029055; Ntn_hydrolases_N.
DR   InterPro; IPR000246; Peptidase_T2.
DR   PANTHER; PTHR10188; PTHR10188; 1.
DR   Pfam; PF01112; Asparaginase_2; 1.
DR   SUPFAM; SSF56235; SSF56235; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Reference proteome; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..397
FT                   /note="L-asparaginase-like protein GD25160"
FT                   /id="PRO_0000384147"
FT   DISULFID        90..95
FT                   /evidence="ECO:0000250|UniProtKB:P20933"
FT   DISULFID        189..205
FT                   /evidence="ECO:0000250|UniProtKB:P20933"
FT   DISULFID        344..371
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   397 AA;  43693 MW;  CBBEFE5C570AD911 CRC64;
     MLAQSCCLRL LILLLLFTSI CSVSKKSLKY FRNRKLRERR IKLFGTKKTE IQSLLISTWN
     YTDANLQAWS VLQQGHRRTR QAVIQGCMAC QNQRCGRLLA GRSSPDTEGA LTLEAAIMDG
     ESLEYGAVAG MDGVRNAILV ADAVLKYTKH SVLVGKSATK FARSLGYKEE YLTDARTKNV
     LKKWSSNGCQ PNFWRDVHPS PAENCGPYSP LPEHLHQHPM HQEYAITQGQ HDQLAFLALD
     AEGKFHVASQ SSGAQFRIPG RVGDSAVPGA GIYADNEVGG AVASGDGDVL MRHLPAFLAV
     EAMRAGKDPD QAAEWVVQRL LRHNTEFNGA VVVVNRRGIY AAACAGLDEF HFVVSGGKEY
     LSMARVERVK CLERENEVID GGPKGLFPTI PEKQKVP