ID   ASPG2_DROYA             Reviewed;         399 AA.
AC   B4P8E0;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 44.
DE   RecName: Full=L-asparaginase-like protein GE13669;
DE   Flags: Precursor;
GN   ORFNames=GE13669;
OS   Drosophila yakuba (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7245;
RN   [1] {ECO:0000312|EMBL:EDW91180.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tai18E2 / Tucson 14021-0261.01 {ECO:0000312|EMBL:EDW91180.1};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the Ntn-hydrolase family. {ECO:0000255}.
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DR   EMBL; CM000158; EDW91180.1; -; Genomic_DNA.
DR   RefSeq; XP_002091468.1; XM_002091432.2.
DR   AlphaFoldDB; B4P8E0; -.
DR   SMR; B4P8E0; -.
DR   STRING; 7245.FBpp0258679; -.
DR   PRIDE; B4P8E0; -.
DR   EnsemblMetazoa; FBtr0260187; FBpp0258679; FBgn0231326.
DR   GeneID; 6530555; -.
DR   KEGG; dya:Dyak_GE13669; -.
DR   eggNOG; KOG1593; Eukaryota.
DR   HOGENOM; CLU_021603_0_0_1; -.
DR   OMA; QAVIQGC; -.
DR   OrthoDB; 1487354at2759; -.
DR   PhylomeDB; B4P8E0; -.
DR   Proteomes; UP000002282; Chromosome 2R.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR029055; Ntn_hydrolases_N.
DR   InterPro; IPR000246; Peptidase_T2.
DR   PANTHER; PTHR10188; PTHR10188; 1.
DR   Pfam; PF01112; Asparaginase_2; 1.
DR   SUPFAM; SSF56235; SSF56235; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..399
FT                   /note="L-asparaginase-like protein GE13669"
FT                   /id="PRO_0000384148"
FT   DISULFID        90..95
FT                   /evidence="ECO:0000250|UniProtKB:P20933"
FT   DISULFID        189..205
FT                   /evidence="ECO:0000250|UniProtKB:P20933"
FT   DISULFID        344..371
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   399 AA;  44077 MW;  00060257A54271A5 CRC64;
     MLAQSCCLRL LILLLLFKST CSVREKSQKY FKNRKLRERR IKLYGTKKTE IQPLLISTWN
     YTDANLQAWS VLQQGPRRTR MAVMQGCMAC QNQRCGRLLA GGSSPDSEGT LTLEAAIMDG
     EHLEYGAVAA MEGARNAILV ADAVLRYTKH SVLVGKSATK FARSLGYKEE FLTDGRTKSV
     WKKWRSNGCQ PNFWRDVRPP PTENCGPYTP LPEHLHQHPM HQEYAITQGQ HDQLAFLALD
     AEGKFHVASQ SSGAQFRIPG RVGDAAVPGA GIYADNDVGG AVASGDGDVL MRHLPAFLAV
     EAMRAGKRPD QAAKWVVQRL LRHNTEFNGA VVVVNRRGIY AAACAGLDEF HFVVSGGKGY
     LIMARVERIK CLERESEVVD DGPKGLFPTI PEKQAVPRG