PCMD1_CHICK
ID PCMD1_CHICK Reviewed; 358 AA.
AC Q5ZMR3;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Protein-L-isoaspartate O-methyltransferase domain-containing protein 1;
GN Name=PCMTD1; ORFNames=RCJMB04_1g9;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT "Characterization of 954 bovine full-CDS cDNA sequences.";
RL BMC Genomics 6:166-166(2005).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family. {ECO:0000305}.
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DR EMBL; AJ719321; CAG30980.1; -; mRNA.
DR RefSeq; NP_001026190.1; NM_001031019.1.
DR RefSeq; XP_015138079.1; XM_015282593.1.
DR RefSeq; XP_015138080.1; XM_015282594.1.
DR AlphaFoldDB; Q5ZMR3; -.
DR SMR; Q5ZMR3; -.
DR STRING; 9031.ENSGALP00000024559; -.
DR PaxDb; Q5ZMR3; -.
DR Ensembl; ENSGALT00000079752; ENSGALP00000056857; ENSGALG00000031035.
DR Ensembl; ENSGALT00000085374; ENSGALP00000062589; ENSGALG00000031035.
DR Ensembl; ENSGALT00000102538; ENSGALP00000073517; ENSGALG00000031035.
DR GeneID; 421114; -.
DR KEGG; gga:421114; -.
DR CTD; 115294; -.
DR VEuPathDB; HostDB:geneid_421114; -.
DR eggNOG; KOG1661; Eukaryota.
DR GeneTree; ENSGT00950000183032; -.
DR HOGENOM; CLU_029295_0_0_1; -.
DR InParanoid; Q5ZMR3; -.
DR OMA; CTWERRD; -.
DR OrthoDB; 1560133at2759; -.
DR PhylomeDB; Q5ZMR3; -.
DR TreeFam; TF329329; -.
DR PRO; PR:Q5ZMR3; -.
DR Proteomes; UP000000539; Chromosome 2.
DR Bgee; ENSGALG00000031035; Expressed in spleen and 13 other tissues.
DR ExpressionAtlas; Q5ZMR3; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IBA:GO_Central.
DR Gene3D; 3.40.50.150; -; 1.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR11579; PTHR11579; 1.
DR SUPFAM; SSF53335; SSF53335; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Lipoprotein; Myristate; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000255"
FT CHAIN 2..358
FT /note="Protein-L-isoaspartate O-methyltransferase domain-
FT containing protein 1"
FT /id="PRO_0000293541"
FT REGION 300..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..335
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 64
FT /evidence="ECO:0000250"
FT LIPID 2
FT /note="N-myristoyl glycine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 358 AA; 40923 MW; 80B7A577A42A2C5F CRC64;
MGGAVSAGED NDDLIDNLKE AQYIRTESVE QAFRAIDRGD YYLEGYRDNA YKDLAWKHGN
IHLSAPCIYS EVMEALKLQP GLSFLNLGSG TGYLSTMVGL ILGPFGINHG IELHSDVVEY
AKEKLESFIK YSDSFDKFEF CEPAFVVGNC LEIASDSHQY DRIYCGAGVQ KDHENYMKIL
LKVGGILVMP IEDQLTQILR TGQNTWESKN ILAVSFAPLV QPNRNDNGKH DTVGLPPCAV
RNLQDLARIY IRRTLRNFIN EEMKAKGIAQ KAPPKRKRRR CRRRRINTYV FVGNQLIPQP
LDSEEDERME DDNKEEEDKD HSEALKPEEP PRNLLREKIM SLPLPESLKA YLTYYREK
