ID   PCNA1_DAUCA             Reviewed;         264 AA.
AC   Q00268;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Proliferating cell nuclear antigen;
DE            Short=PCNA;
DE   AltName: Full=Cyclin;
OS   Daucus carota (Wild carrot).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Apiales; Apiaceae; Apioideae; Scandiceae; Daucinae;
OC   Daucus; Daucus sect. Daucus.
OX   NCBI_TaxID=4039;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Kurodagosun;
RX   PubMed=1346518; DOI=10.1111/j.1432-1033.1992.tb16559.x;
RA   Hata S., Kouchi H., Tanaka Y., Minami E., Matsumoto T., Suzuka I.,
RA   Hashimoto J.;
RT   "Identification of carrot cDNA clones encoding a second putative
RT   proliferating cell-nuclear antigen, DNA polymerase delta auxiliary
RT   protein.";
RL   Eur. J. Biochem. 203:367-371(1992).
CC   -!- FUNCTION: This protein is an auxiliary protein of DNA polymerase delta
CC       and is involved in the control of eukaryotic DNA replication by
CC       increasing the polymerase's processibility during elongation of the
CC       leading strand.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000305}.
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DR   EMBL; D10555; BAA01412.1; -; Genomic_DNA.
DR   PIR; PQ0337; PQ0337.
DR   PIR; S20592; S20592.
DR   AlphaFoldDB; Q00268; -.
DR   SMR; Q00268; -.
DR   PRIDE; Q00268; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0070207; P:protein homotrimerization; IEA:EnsemblPlants.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   HAMAP; MF_00317; DNApol_clamp_arch; 1.
DR   InterPro; IPR000730; Pr_cel_nuc_antig.
DR   InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR   InterPro; IPR022659; Pr_cel_nuc_antig_CS.
DR   InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR   Pfam; PF02747; PCNA_C; 1.
DR   Pfam; PF00705; PCNA_N; 1.
DR   PRINTS; PR00339; PCNACYCLIN.
DR   TIGRFAMs; TIGR00590; pcna; 1.
DR   PROSITE; PS01251; PCNA_1; 1.
DR   PROSITE; PS00293; PCNA_2; 1.
PE   3: Inferred from homology;
KW   DNA replication; DNA-binding; Nucleus.
FT   CHAIN           1..264
FT                   /note="Proliferating cell nuclear antigen"
FT                   /id="PRO_0000149181"
FT   DNA_BIND        61..80
FT                   /evidence="ECO:0000255"
FT   VARIANT         218
FT                   /note="A -> L"
SQ   SEQUENCE   264 AA;  29195 MW;  87E3A0FCB4B26EF0 CRC64;
     MLELRLVQGS LLKKVMDSIK DLVNDANFDC SATGFSLQAM DSSHVALVAV LLRSEGFEHY
     RCDRNISMGM NLGNMAKMLK CAGNDDIITI KADDGSDTVT FMFESPTQDK IADFEMKLMD
     IDSEHLGIPE AEYHAIVRMP SAEFARICKD LSSIGDTVVI SVTKEGVKFS TRGDIGTANI
     VCRQNTTVDK PEEATVIEMN EPVSLTFALR YMNSFTKASP LSSTVTISLS SELPVVVEYK
     IAEMGYIRFY LAPKIEEEED ESKP