ID   PCNA1_SULOH             Reviewed;         245 AA.
AC   P57762;
DT   21-FEB-2001, integrated into UniProtKB/Swiss-Prot.
DT   21-FEB-2001, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=DNA polymerase sliding clamp 1 {ECO:0000255|HAMAP-Rule:MF_00317};
DE   AltName: Full=Proliferating cell nuclear antigen homolog 1 {ECO:0000255|HAMAP-Rule:MF_00317};
DE            Short=PCNA 1 {ECO:0000255|HAMAP-Rule:MF_00317};
GN   Name=pcn1 {ECO:0000255|HAMAP-Rule:MF_00317}; Synonyms=pcnAA;
OS   Sulfurisphaera ohwakuensis.
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfurisphaera.
OX   NCBI_TaxID=69656;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=TA-1;
RX   PubMed=11139078; DOI=10.1007/s007920070005;
RA   Iwai T., Kurosawa N., Itoh Y.H., Horiuchi T.;
RT   "Phylogenetic analysis of archaeal PCNA homologues.";
RL   Extremophiles 4:357-364(2000).
CC   -!- FUNCTION: Sliding clamp subunit that acts as a moving platform for DNA
CC       processing. Responsible for tethering the catalytic subunit of DNA
CC       polymerase and other proteins to DNA during high-speed replication.
CC       {ECO:0000255|HAMAP-Rule:MF_00317}.
CC   -!- SUBUNIT: Homotrimer. The subunits circularize to form a toroid; DNA
CC       passes through its center. Replication factor C (RFC) is required to
CC       load the toroid on the DNA. {ECO:0000255|HAMAP-Rule:MF_00317}.
CC   -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00317}.
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DR   EMBL; AB045089; BAB19661.1; -; Genomic_DNA.
DR   AlphaFoldDB; P57762; -.
DR   SMR; P57762; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00317; DNApol_clamp_arch; 1.
DR   InterPro; IPR000730; Pr_cel_nuc_antig.
DR   InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR   InterPro; IPR022659; Pr_cel_nuc_antig_CS.
DR   InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR   PANTHER; PTHR11352:SF0; PTHR11352:SF0; 1.
DR   Pfam; PF02747; PCNA_C; 1.
DR   Pfam; PF00705; PCNA_N; 1.
DR   PRINTS; PR00339; PCNACYCLIN.
DR   TIGRFAMs; TIGR00590; pcna; 1.
DR   PROSITE; PS01251; PCNA_1; 1.
PE   3: Inferred from homology;
KW   DNA replication; DNA-binding.
FT   CHAIN           1..245
FT                   /note="DNA polymerase sliding clamp 1"
FT                   /id="PRO_0000149212"
SQ   SEQUENCE   245 AA;  27380 MW;  7CBA8E0F6024D7D0 CRC64;
     MRIVYDDVRD LKAIVQALLK LVDEALFDIK PEGIQLVAID KAHISLIKIE LPKEMFKEYD
     VPEEFKFGFN TQYMSKLLKA AKRKEEIIIE ADSPEVVKLT LSGALNRVFN VNNIEVLPPE
     VPEVNLEFDI KATINASGFK NAIGEIAEVA DTLLISANEE KVIVKGEGEN KVEVEFSKDT
     GSLADIEFNK ESSSAYDVEY LNDIISLTKL SDYVKVAFAE QKPMQLEFNM EGGGKVTYLL
     APKLS