ID   PCNA3_AERPE             Reviewed;         249 AA.
AC   Q9YEZ5;
DT   21-FEB-2001, integrated into UniProtKB/Swiss-Prot.
DT   21-FEB-2001, sequence version 2.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=DNA polymerase sliding clamp 3 {ECO:0000255|HAMAP-Rule:MF_00317};
DE   AltName: Full=DNA polymerase sliding clamp B2 {ECO:0000255|HAMAP-Rule:MF_00317};
DE   AltName: Full=Proliferating cell nuclear antigen homolog 3 {ECO:0000255|HAMAP-Rule:MF_00317};
DE            Short=PCNA 3 {ECO:0000255|HAMAP-Rule:MF_00317};
GN   Name=pcn3 {ECO:0000255|HAMAP-Rule:MF_00317}; Synonyms=pcnB2;
GN   OrderedLocusNames=APE_0441.1;
OS   Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 /
OS   K1).
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC   Desulfurococcaceae; Aeropyrum.
OX   NCBI_TaxID=272557;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1;
RX   PubMed=10382966; DOI=10.1093/dnares/6.2.83;
RA   Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K.,
RA   Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A.,
RA   Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S.,
RA   Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A.,
RA   Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H.;
RT   "Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon,
RT   Aeropyrum pernix K1.";
RL   DNA Res. 6:83-101(1999).
CC   -!- FUNCTION: Sliding clamp subunit that acts as a moving platform for DNA
CC       processing. Responsible for tethering the catalytic subunit of DNA
CC       polymerase and other proteins to DNA during high-speed replication.
CC       {ECO:0000255|HAMAP-Rule:MF_00317}.
CC   -!- SUBUNIT: Homotrimer. The subunits circularize to form a toroid; DNA
CC       passes through its center. Replication factor C (RFC) is required to
CC       load the toroid on the DNA. {ECO:0000255|HAMAP-Rule:MF_00317}.
CC   -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00317}.
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DR   EMBL; BA000002; BAA79401.2; -; Genomic_DNA.
DR   PIR; E72738; E72738.
DR   AlphaFoldDB; Q9YEZ5; -.
DR   SMR; Q9YEZ5; -.
DR   STRING; 272557.APE_0441.1; -.
DR   EnsemblBacteria; BAA79401; BAA79401; APE_0441.1.
DR   KEGG; ape:APE_0441.1; -.
DR   eggNOG; arCOG00488; Archaea.
DR   OMA; EMKLINM; -.
DR   Proteomes; UP000002518; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00317; DNApol_clamp_arch; 1.
DR   InterPro; IPR000730; Pr_cel_nuc_antig.
DR   InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR   InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR   PANTHER; PTHR11352:SF0; PTHR11352:SF0; 1.
DR   Pfam; PF02747; PCNA_C; 1.
DR   Pfam; PF00705; PCNA_N; 1.
DR   PRINTS; PR00339; PCNACYCLIN.
PE   3: Inferred from homology;
KW   DNA replication; DNA-binding; Reference proteome.
FT   CHAIN           1..249
FT                   /note="DNA polymerase sliding clamp 3"
FT                   /id="PRO_0000149191"
SQ   SEQUENCE   249 AA;  27935 MW;  E84D470C59FA8EDF CRC64;
     MADARFYFSD ARTWRYMVAS IEKIIEEGVF VATGEGLSLR ALDTSHVAMV DLYYPNTAFI
     EYDIGGESVE FGVSFDLLSK VLRRARKEDE LVLEVEGSRL AVKLKSRGER TFRIPQVVMT
     YEKLPEPKVS FTVRARMLGS TFREAVRDLE PHSETLTLRA LEDALLLVGS SEMATVEIEL
     SQSRGSLLDY EAESQDRASY SIEYFSEMLS AAQAADAVVV SFSEDAPVRV DMEYLGGGRL
     TFYVSPKIE