ID   PCNA_BRANA              Reviewed;         263 AA.
AC   Q43124;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Proliferating cell nuclear antigen;
DE            Short=PCNA;
OS   Brassica napus (Rape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX   NCBI_TaxID=3708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Westar;
RX   PubMed=8102346; DOI=10.1139/g93-063;
RA   Markley N.A., Bonham-Smith P.C., Moloney M.M.;
RT   "Molecular cloning and expression of a cDNA encoding the proliferating cell
RT   nuclear antigen from Brassica napus (oilseed rape).";
RL   Genome 36:459-466(1993).
CC   -!- FUNCTION: This protein is an auxiliary protein of DNA polymerase delta
CC       and is involved in the control of eukaryotic DNA replication by
CC       increasing the polymerase's processibility during elongation of the
CC       leading strand. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000305}.
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DR   EMBL; S64617; AAB27811.1; -; mRNA.
DR   PIR; T09523; T09523.
DR   RefSeq; NP_001303041.1; NM_001316112.1.
DR   AlphaFoldDB; Q43124; -.
DR   SMR; Q43124; -.
DR   EnsemblPlants; CDY06251; CDY06251; GSBRNA2T00122168001.
DR   EnsemblPlants; CDY09923; CDY09923; GSBRNA2T00031690001.
DR   GeneID; 106420145; -.
DR   Gramene; CDY06251; CDY06251; GSBRNA2T00122168001.
DR   Gramene; CDY09923; CDY09923; GSBRNA2T00031690001.
DR   KEGG; bna:106420145; -.
DR   OMA; EMKLINM; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   HAMAP; MF_00317; DNApol_clamp_arch; 1.
DR   InterPro; IPR000730; Pr_cel_nuc_antig.
DR   InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR   InterPro; IPR022659; Pr_cel_nuc_antig_CS.
DR   InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR   Pfam; PF02747; PCNA_C; 1.
DR   Pfam; PF00705; PCNA_N; 1.
DR   PRINTS; PR00339; PCNACYCLIN.
DR   TIGRFAMs; TIGR00590; pcna; 1.
DR   PROSITE; PS01251; PCNA_1; 1.
DR   PROSITE; PS00293; PCNA_2; 1.
PE   2: Evidence at transcript level;
KW   DNA replication; DNA-binding; Nucleus.
FT   CHAIN           1..263
FT                   /note="Proliferating cell nuclear antigen"
FT                   /id="PRO_0000149179"
FT   DNA_BIND        61..80
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   263 AA;  29165 MW;  3C5FB98B4A787A8C CRC64;
     MLELRLVQGS LLKKVLESIK DLVNDANFDC STTGFSLQAM DSSHVALVSL LLRSEGFEHY
     RCDRNLSMGM NLGNMSKMLK CAGNDDIITI KADDGGDTVT FMFESPKQDK IADFEMKLMD
     IDSEHLGIPD AEYHSIVRMP SNEFSRICKD LSTIGDTVVI SVTKEGVKFS TAGDIGTANI
     VLRQNTTVDK PEDAIVIEMN EPVSLSFALR YMNSFTKATP LSDTVTISLS SELPVVVEYK
     VAEMGYIRYY LAPKIEEDEE DKA