ID   PCNA_CENSY              Reviewed;         248 AA.
AC   A0RXH7;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=DNA polymerase sliding clamp {ECO:0000255|HAMAP-Rule:MF_00317};
DE   AltName: Full=Proliferating cell nuclear antigen homolog {ECO:0000255|HAMAP-Rule:MF_00317};
DE            Short=PCNA {ECO:0000255|HAMAP-Rule:MF_00317};
GN   Name=pcn {ECO:0000255|HAMAP-Rule:MF_00317}; OrderedLocusNames=CENSYa_1422;
OS   Cenarchaeum symbiosum (strain A).
OC   Archaea; Thaumarchaeota; Cenarchaeales; Cenarchaeaceae; Cenarchaeum.
OX   NCBI_TaxID=414004;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A;
RX   PubMed=17114289; DOI=10.1073/pnas.0608549103;
RA   Hallam S.J., Konstantinidis K.T., Putnam N., Schleper C., Watanabe Y.,
RA   Sugahara J., Preston C., de la Torre J., Richardson P.M., DeLong E.F.;
RT   "Genomic analysis of the uncultivated marine crenarchaeote Cenarchaeum
RT   symbiosum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:18296-18301(2006).
CC   -!- FUNCTION: Sliding clamp subunit that acts as a moving platform for DNA
CC       processing. Responsible for tethering the catalytic subunit of DNA
CC       polymerase and other proteins to DNA during high-speed replication.
CC       {ECO:0000255|HAMAP-Rule:MF_00317}.
CC   -!- SUBUNIT: Homotrimer. The subunits circularize to form a toroid; DNA
CC       passes through its center. Replication factor C (RFC) is required to
CC       load the toroid on the DNA. {ECO:0000255|HAMAP-Rule:MF_00317}.
CC   -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00317}.
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DR   EMBL; DP000238; ABK78044.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0RXH7; -.
DR   SMR; A0RXH7; -.
DR   STRING; 414004.CENSYa_1422; -.
DR   EnsemblBacteria; ABK78044; ABK78044; CENSYa_1422.
DR   KEGG; csy:CENSYa_1422; -.
DR   PATRIC; fig|414004.10.peg.1305; -.
DR   HOGENOM; CLU_043978_3_0_2; -.
DR   OMA; EMKLINM; -.
DR   Proteomes; UP000000758; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00317; DNApol_clamp_arch; 1.
DR   InterPro; IPR000730; Pr_cel_nuc_antig.
DR   InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR   InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR   PANTHER; PTHR11352:SF0; PTHR11352:SF0; 1.
DR   Pfam; PF02747; PCNA_C; 1.
DR   Pfam; PF00705; PCNA_N; 1.
DR   PRINTS; PR00339; PCNACYCLIN.
DR   TIGRFAMs; TIGR00590; pcna; 1.
PE   3: Inferred from homology;
KW   DNA replication; DNA-binding; Reference proteome.
FT   CHAIN           1..248
FT                   /note="DNA polymerase sliding clamp"
FT                   /id="PRO_0000336043"
SQ   SEQUENCE   248 AA;  26925 MW;  2E29A8E8DB07E5A5 CRC64;
     MAFSAKTSGS DDLKAIISAI STLVEEATFV ATAEGITFRG MDPSHVALID ISWPNSAFEK
     YECDSNIKFG VRIDEFTKLI KRADKKDSIT ISVSKDSMLL IDIGSNKKYK IRLIESSATD
     TPLPKISYDA KIELATTSFE KILGDVQVVS DYLTIKAKPT GVEFAGKGDS GEAAIDVKKD
     DDSMEALKVK KESEGTYSLE YLNPIVRAVG GAAGSVTCEF SDAKPLRVEF KVANIGRIHF
     YLAPRVSS