ID   PCNA_HALMA              Reviewed;         247 AA.
AC   Q9P9H8; Q5UYQ1;
DT   21-FEB-2001, integrated into UniProtKB/Swiss-Prot.
DT   21-FEB-2001, sequence version 2.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=DNA polymerase sliding clamp {ECO:0000255|HAMAP-Rule:MF_00317};
DE   AltName: Full=Proliferating cell nuclear antigen homolog {ECO:0000255|HAMAP-Rule:MF_00317};
DE            Short=PCNA {ECO:0000255|HAMAP-Rule:MF_00317};
GN   Name=pcn {ECO:0000255|HAMAP-Rule:MF_00317}; Synonyms=pcnA;
GN   OrderedLocusNames=rrnAC2851;
OS   Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS   B-1809) (Halobacterium marismortui).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=272569;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Ichiki H., Tanaka Y., Mochizuki K., Yoshimatsu K., Sakurai T., Fujiwara T.;
RT   "Molecular and genetic analysis of copper-containing dissimilatory nitrite
RT   reductase from a denitrifying halophilic archaeon, Haloarcula
RT   marismortui.";
RL   Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809;
RX   PubMed=15520287; DOI=10.1101/gr.2700304;
RA   Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA   Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA   Hood L., Ng W.V.;
RT   "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT   Dead Sea.";
RL   Genome Res. 14:2221-2234(2004).
CC   -!- FUNCTION: Sliding clamp subunit that acts as a moving platform for DNA
CC       processing. Responsible for tethering the catalytic subunit of DNA
CC       polymerase and other proteins to DNA during high-speed replication.
CC       {ECO:0000255|HAMAP-Rule:MF_00317}.
CC   -!- SUBUNIT: Homotrimer. The subunits circularize to form a toroid; DNA
CC       passes through its center. Replication factor C (RFC) is required to
CC       load the toroid on the DNA. {ECO:0000255|HAMAP-Rule:MF_00317}.
CC   -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00317}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAV47602.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=CAB93143.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AJ278286; CAB93143.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AY596297; AAV47602.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_007187874.1; NZ_CP039138.1.
DR   AlphaFoldDB; Q9P9H8; -.
DR   SMR; Q9P9H8; -.
DR   STRING; 272569.rrnAC2851; -.
DR   EnsemblBacteria; AAV47602; AAV47602; rrnAC2851.
DR   GeneID; 40153699; -.
DR   KEGG; hma:rrnAC2851; -.
DR   PATRIC; fig|272569.17.peg.3422; -.
DR   eggNOG; arCOG00488; Archaea.
DR   HOGENOM; CLU_043978_1_1_2; -.
DR   Proteomes; UP000001169; Chromosome I.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00317; DNApol_clamp_arch; 1.
DR   InterPro; IPR000730; Pr_cel_nuc_antig.
DR   InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR   InterPro; IPR022659; Pr_cel_nuc_antig_CS.
DR   InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR   PANTHER; PTHR11352:SF0; PTHR11352:SF0; 1.
DR   Pfam; PF02747; PCNA_C; 1.
DR   Pfam; PF00705; PCNA_N; 1.
DR   PRINTS; PR00339; PCNACYCLIN.
DR   PROSITE; PS01251; PCNA_1; 1.
PE   3: Inferred from homology;
KW   DNA replication; DNA-binding; Reference proteome.
FT   CHAIN           1..247
FT                   /note="DNA polymerase sliding clamp"
FT                   /id="PRO_0000149193"
SQ   SEQUENCE   247 AA;  27060 MW;  12EB3E2774A7FB3A CRC64;
     MFNAIVSADT LQATLDSVSV LVDECKIHLE EDGLEIRAVD PANVGMVDLR LDAAAFESYE
     TDGGLIGVNL SRLEDIAGMA DAGQLVHLDL DEETRKLHIS IDGLEYTLAL IDPDSIRQEP
     DLPDLDLSAN IVIEGKDIDR SVTAADMVSD HIALGVDATD ELFYVDAEGD TDDVHLELTR
     DDLIDLTPGD AHSLFSLDYL KNMNKAIPKD AEVEMELGEE FPVKMHFSFA EGQGRVTYML
     APRIQSE