ID   PCNA_HALS3              Reviewed;         247 AA.
AC   B0R7F7;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=DNA polymerase sliding clamp {ECO:0000255|HAMAP-Rule:MF_00317};
DE   AltName: Full=Proliferating cell nuclear antigen homolog {ECO:0000255|HAMAP-Rule:MF_00317};
DE            Short=PCNA {ECO:0000255|HAMAP-Rule:MF_00317};
GN   Name=pcn {ECO:0000255|HAMAP-Rule:MF_00317}; OrderedLocusNames=OE_4165R;
OS   Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=478009;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29341 / DSM 671 / R1;
RX   PubMed=18313895; DOI=10.1016/j.ygeno.2008.01.001;
RA   Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K.,
RA   Ruepp A., Soppa J., Tittor J., Oesterhelt D.;
RT   "Evolution in the laboratory: the genome of Halobacterium salinarum strain
RT   R1 compared to that of strain NRC-1.";
RL   Genomics 91:335-346(2008).
CC   -!- FUNCTION: Sliding clamp subunit that acts as a moving platform for DNA
CC       processing. Responsible for tethering the catalytic subunit of DNA
CC       polymerase and other proteins to DNA during high-speed replication.
CC       {ECO:0000255|HAMAP-Rule:MF_00317}.
CC   -!- SUBUNIT: Homotrimer. The subunits circularize to form a toroid; DNA
CC       passes through its center. Replication factor C (RFC) is required to
CC       load the toroid on the DNA. {ECO:0000255|HAMAP-Rule:MF_00317}.
CC   -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00317}.
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DR   EMBL; AM774415; CAP14676.1; -; Genomic_DNA.
DR   RefSeq; WP_010903677.1; NC_010364.1.
DR   AlphaFoldDB; B0R7F7; -.
DR   SMR; B0R7F7; -.
DR   EnsemblBacteria; CAP14676; CAP14676; OE_4165R.
DR   GeneID; 5953309; -.
DR   GeneID; 62887537; -.
DR   KEGG; hsl:OE_4165R; -.
DR   HOGENOM; CLU_043978_1_1_2; -.
DR   OMA; EMKLINM; -.
DR   PhylomeDB; B0R7F7; -.
DR   Proteomes; UP000001321; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00317; DNApol_clamp_arch; 1.
DR   InterPro; IPR000730; Pr_cel_nuc_antig.
DR   InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR   InterPro; IPR022659; Pr_cel_nuc_antig_CS.
DR   InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR   PANTHER; PTHR11352:SF0; PTHR11352:SF0; 1.
DR   Pfam; PF02747; PCNA_C; 1.
DR   Pfam; PF00705; PCNA_N; 1.
DR   PRINTS; PR00339; PCNACYCLIN.
DR   PROSITE; PS01251; PCNA_1; 1.
PE   3: Inferred from homology;
KW   DNA replication; DNA-binding.
FT   CHAIN           1..247
FT                   /note="DNA polymerase sliding clamp"
FT                   /id="PRO_1000115814"
SQ   SEQUENCE   247 AA;  26824 MW;  B1506BBD54851544 CRC64;
     MFKAIVSADT LQETLDSVSV LVDECKIHLD DDTLSIRAVD PASVGMVDLD LAATAFESYE
     ADGGLIGVNL SRLEDIAGMA DAGQLIQLEL DEETRKLHIQ IDGLEYTLAL IDPDSIRQEP
     DIPDLDLPAH VAIEGRDIDR AVTAADMVSD HIALGVDTGD DLFYVNAEGD TDDVHLELAP
     DQLIDLDAGD AHSLFSLDYL KDMNKAIPTT AEVELELGDE FPIKLHFDIA DAQGHVTYML
     APRIQSN