PCNA_MAIZE
ID PCNA_MAIZE Reviewed; 263 AA.
AC Q43266;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Proliferating cell nuclear antigen;
DE Short=PCNA;
GN Name=PCNA;
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Black Mexican Sweet;
RX PubMed=7999788; DOI=10.1016/0167-4781(94)00192-6;
RA Lopez I., Khan S., Vasquez-Ramos J., Hussey P.J.;
RT "Molecular cloning of a maize cDNA clone encoding a putative proliferating
RT cell nuclear antigen.";
RL Biochim. Biophys. Acta 1260:119-121(1995).
CC -!- FUNCTION: This protein is an auxiliary protein of DNA polymerase delta
CC and is involved in the control of eukaryotic DNA replication by
CC increasing the polymerase's processibility during elongation of the
CC leading strand. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000305}.
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DR EMBL; X79065; CAA55669.1; -; mRNA.
DR PIR; S52115; S52115.
DR RefSeq; NP_001105461.1; NM_001111991.1.
DR AlphaFoldDB; Q43266; -.
DR SMR; Q43266; -.
DR BioGRID; 951642; 1.
DR STRING; 4577.GRMZM2G030523_P01; -.
DR PaxDb; Q43266; -.
DR PRIDE; Q43266; -.
DR EnsemblPlants; Zm00001eb258230_T001; Zm00001eb258230_P001; Zm00001eb258230.
DR GeneID; 542425; -.
DR Gramene; Zm00001eb258230_T001; Zm00001eb258230_P001; Zm00001eb258230.
DR KEGG; zma:542425; -.
DR MaizeGDB; 113516; -.
DR eggNOG; KOG1636; Eukaryota.
DR HOGENOM; CLU_043978_3_0_1; -.
DR OMA; EMKLINM; -.
DR OrthoDB; 1012066at2759; -.
DR Proteomes; UP000007305; Chromosome 5.
DR ExpressionAtlas; Q43266; baseline and differential.
DR Genevisible; Q43266; ZM.
DR GO; GO:0043626; C:PCNA complex; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030337; F:DNA polymerase processivity factor activity; IBA:GO_Central.
DR GO; GO:0006272; P:leading strand elongation; IBA:GO_Central.
DR GO; GO:0006298; P:mismatch repair; IBA:GO_Central.
DR GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR GO; GO:0019985; P:translesion synthesis; IBA:GO_Central.
DR HAMAP; MF_00317; DNApol_clamp_arch; 1.
DR InterPro; IPR000730; Pr_cel_nuc_antig.
DR InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR InterPro; IPR022659; Pr_cel_nuc_antig_CS.
DR InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR Pfam; PF02747; PCNA_C; 1.
DR Pfam; PF00705; PCNA_N; 1.
DR PRINTS; PR00339; PCNACYCLIN.
DR TIGRFAMs; TIGR00590; pcna; 1.
DR PROSITE; PS01251; PCNA_1; 1.
DR PROSITE; PS00293; PCNA_2; 1.
PE 2: Evidence at transcript level;
KW DNA replication; DNA-binding; Nucleus; Reference proteome.
FT CHAIN 1..263
FT /note="Proliferating cell nuclear antigen"
FT /id="PRO_0000149183"
FT DNA_BIND 61..80
FT /evidence="ECO:0000255"
SQ SEQUENCE 263 AA; 29343 MW; 450E55EC484BD5A6 CRC64;
MLELRLVQGS LLKKVLEAIR ELVNDANFDC SGTGFSLQAM DSSHVALVAL LLRAEGFEHY
RCDRNLSMGM NLNNMAKMLR CAGNDDIITI KADDGSDTVT FMFESPKQDK IADFEMKLMD
IDSEHLGIPD SEYQAIVRMP SSEFMRICKD LSSIGDTVVI SVTKEGVKFS TSGEIGSANI
VCRQNQTIDK PEEATIIEMQ EPVSLTFALR YMNSFTKASS LSEQVTISLS SELPVVVEYK
IAEMGYIRFY LAPKIEDDEE MKP