位置:首页 > 蛋白库 > PCNA_MAIZE
PCNA_MAIZE
ID   PCNA_MAIZE              Reviewed;         263 AA.
AC   Q43266;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Proliferating cell nuclear antigen;
DE            Short=PCNA;
GN   Name=PCNA;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Black Mexican Sweet;
RX   PubMed=7999788; DOI=10.1016/0167-4781(94)00192-6;
RA   Lopez I., Khan S., Vasquez-Ramos J., Hussey P.J.;
RT   "Molecular cloning of a maize cDNA clone encoding a putative proliferating
RT   cell nuclear antigen.";
RL   Biochim. Biophys. Acta 1260:119-121(1995).
CC   -!- FUNCTION: This protein is an auxiliary protein of DNA polymerase delta
CC       and is involved in the control of eukaryotic DNA replication by
CC       increasing the polymerase's processibility during elongation of the
CC       leading strand. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X79065; CAA55669.1; -; mRNA.
DR   PIR; S52115; S52115.
DR   RefSeq; NP_001105461.1; NM_001111991.1.
DR   AlphaFoldDB; Q43266; -.
DR   SMR; Q43266; -.
DR   BioGRID; 951642; 1.
DR   STRING; 4577.GRMZM2G030523_P01; -.
DR   PaxDb; Q43266; -.
DR   PRIDE; Q43266; -.
DR   EnsemblPlants; Zm00001eb258230_T001; Zm00001eb258230_P001; Zm00001eb258230.
DR   GeneID; 542425; -.
DR   Gramene; Zm00001eb258230_T001; Zm00001eb258230_P001; Zm00001eb258230.
DR   KEGG; zma:542425; -.
DR   MaizeGDB; 113516; -.
DR   eggNOG; KOG1636; Eukaryota.
DR   HOGENOM; CLU_043978_3_0_1; -.
DR   OMA; EMKLINM; -.
DR   OrthoDB; 1012066at2759; -.
DR   Proteomes; UP000007305; Chromosome 5.
DR   ExpressionAtlas; Q43266; baseline and differential.
DR   Genevisible; Q43266; ZM.
DR   GO; GO:0043626; C:PCNA complex; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IBA:GO_Central.
DR   GO; GO:0006272; P:leading strand elongation; IBA:GO_Central.
DR   GO; GO:0006298; P:mismatch repair; IBA:GO_Central.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   GO; GO:0019985; P:translesion synthesis; IBA:GO_Central.
DR   HAMAP; MF_00317; DNApol_clamp_arch; 1.
DR   InterPro; IPR000730; Pr_cel_nuc_antig.
DR   InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR   InterPro; IPR022659; Pr_cel_nuc_antig_CS.
DR   InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR   Pfam; PF02747; PCNA_C; 1.
DR   Pfam; PF00705; PCNA_N; 1.
DR   PRINTS; PR00339; PCNACYCLIN.
DR   TIGRFAMs; TIGR00590; pcna; 1.
DR   PROSITE; PS01251; PCNA_1; 1.
DR   PROSITE; PS00293; PCNA_2; 1.
PE   2: Evidence at transcript level;
KW   DNA replication; DNA-binding; Nucleus; Reference proteome.
FT   CHAIN           1..263
FT                   /note="Proliferating cell nuclear antigen"
FT                   /id="PRO_0000149183"
FT   DNA_BIND        61..80
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   263 AA;  29343 MW;  450E55EC484BD5A6 CRC64;
     MLELRLVQGS LLKKVLEAIR ELVNDANFDC SGTGFSLQAM DSSHVALVAL LLRAEGFEHY
     RCDRNLSMGM NLNNMAKMLR CAGNDDIITI KADDGSDTVT FMFESPKQDK IADFEMKLMD
     IDSEHLGIPD SEYQAIVRMP SSEFMRICKD LSSIGDTVVI SVTKEGVKFS TSGEIGSANI
     VCRQNQTIDK PEEATIIEMQ EPVSLTFALR YMNSFTKASS LSEQVTISLS SELPVVVEYK
     IAEMGYIRFY LAPKIEDDEE MKP
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024