ID   PCNA_METAR              Reviewed;         246 AA.
AC   Q0W2J4;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=DNA polymerase sliding clamp {ECO:0000255|HAMAP-Rule:MF_00317};
DE   AltName: Full=Proliferating cell nuclear antigen homolog {ECO:0000255|HAMAP-Rule:MF_00317};
DE            Short=PCNA {ECO:0000255|HAMAP-Rule:MF_00317};
GN   Name=pcn {ECO:0000255|HAMAP-Rule:MF_00317}; OrderedLocusNames=UNCMA_08530;
GN   ORFNames=RCIX2293;
OS   Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanocellales; Methanocellaceae; Methanocella.
OX   NCBI_TaxID=351160;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22066 / NBRC 105507 / MRE50;
RX   PubMed=16857943; DOI=10.1126/science.1127062;
RA   Erkel C., Kube M., Reinhardt R., Liesack W.;
RT   "Genome of rice cluster I archaea -- the key methane producers in the rice
RT   rhizosphere.";
RL   Science 313:370-372(2006).
CC   -!- FUNCTION: Sliding clamp subunit that acts as a moving platform for DNA
CC       processing. Responsible for tethering the catalytic subunit of DNA
CC       polymerase and other proteins to DNA during high-speed replication.
CC       {ECO:0000255|HAMAP-Rule:MF_00317}.
CC   -!- SUBUNIT: Homotrimer. The subunits circularize to form a toroid; DNA
CC       passes through its center. Replication factor C (RFC) is required to
CC       load the toroid on the DNA. {ECO:0000255|HAMAP-Rule:MF_00317}.
CC   -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00317}.
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DR   EMBL; AM114193; CAJ37399.1; -; Genomic_DNA.
DR   RefSeq; WP_012035182.1; NC_009464.1.
DR   AlphaFoldDB; Q0W2J4; -.
DR   SMR; Q0W2J4; -.
DR   STRING; 351160.RCIX2293; -.
DR   EnsemblBacteria; CAJ37399; CAJ37399; RCIX2293.
DR   GeneID; 5143526; -.
DR   KEGG; rci:RCIX2293; -.
DR   PATRIC; fig|351160.9.peg.883; -.
DR   eggNOG; arCOG00488; Archaea.
DR   OMA; TIRKDPN; -.
DR   OrthoDB; 70433at2157; -.
DR   Proteomes; UP000000663; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00317; DNApol_clamp_arch; 1.
DR   InterPro; IPR000730; Pr_cel_nuc_antig.
DR   InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR   InterPro; IPR022659; Pr_cel_nuc_antig_CS.
DR   InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR   PANTHER; PTHR11352:SF0; PTHR11352:SF0; 1.
DR   Pfam; PF02747; PCNA_C; 1.
DR   Pfam; PF00705; PCNA_N; 1.
DR   PRINTS; PR00339; PCNACYCLIN.
DR   PROSITE; PS01251; PCNA_1; 1.
PE   3: Inferred from homology;
KW   DNA replication; DNA-binding; Reference proteome.
FT   CHAIN           1..246
FT                   /note="DNA polymerase sliding clamp"
FT                   /id="PRO_1000019179"
SQ   SEQUENCE   246 AA;  26901 MW;  BE94F3199CFDF58D CRC64;
     MFKAAINAEV FKDAIEAVST LVDEAKFRIT KDSISARAVD PANVAMVAFD LNAKAFDTFE
     ATDGEIGIDL VRFMDILGMT ARDDRLELNL NEETRKLEIR TGGLAYTLSL LDPGSIRKEP
     KVPALELPGK IVLNGAELKR AVKAAEKVSD HMALGVQDKT FYVEAEGDLD KVRLEIPESN
     LISLQATSNV RSLFSLDYLN DIVKSLGKAE QVTIDLGTDY PVKFTFSIAS GNGTVIYLLA
     PRIESE