ID   PCNA_MIMIV              Reviewed;         464 AA.
AC   Q7T6Y0;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 2.
DT   02-JUN-2021, entry version 64.
DE   RecName: Full=Probable DNA polymerase sliding clamp;
DE   AltName: Full=Proliferating cell nuclear antigen homolog;
DE            Short=PCNA;
GN   Name=PCNA; OrderedLocusNames=MIMI_R493;
OS   Acanthamoeba polyphaga mimivirus (APMV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Imitervirales; Mimiviridae; Mimivirus.
OX   NCBI_TaxID=212035;
OH   NCBI_TaxID=5757; Acanthamoeba polyphaga (Amoeba).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rowbotham-Bradford;
RX   PubMed=15486256; DOI=10.1126/science.1101485;
RA   Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H.,
RA   La Scola B., Susan M., Claverie J.-M.;
RT   "The 1.2-megabase genome sequence of Mimivirus.";
RL   Science 306:1344-1350(2004).
CC   -!- FUNCTION: Sliding clamp subunit. Responsible for tethering the
CC       catalytic subunit of DNA polymerase to DNA during high-speed
CC       replication (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000305}.
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DR   EMBL; AY653733; AAQ09580.2; -; Genomic_DNA.
DR   RefSeq; YP_003987005.1; NC_014649.1.
DR   SMR; Q7T6Y0; -.
DR   GeneID; 9925123; -.
DR   KEGG; vg:9925123; -.
DR   Proteomes; UP000001134; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   InterPro; IPR000730; Pr_cel_nuc_antig.
DR   InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR   InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR   PANTHER; PTHR11352:SF0; PTHR11352:SF0; 1.
DR   Pfam; PF02747; PCNA_C; 1.
DR   Pfam; PF00705; PCNA_N; 1.
PE   3: Inferred from homology;
KW   DNA replication; DNA-binding; Reference proteome.
FT   CHAIN           1..464
FT                   /note="Probable DNA polymerase sliding clamp"
FT                   /id="PRO_0000149225"
FT   REGION          1..168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          210..239
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..42
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        43..75
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        113..135
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        136..168
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        210..235
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   464 AA;  52303 MW;  E812981E919B56CE CRC64;
     MSKKTGTKTS KSGSKKSNKD VEKLVDDEDI QDLSDKKNKI SQSKNLVKNN KSSKNSKSSK
     SVKSTKTSTK TSLKKQVKTP PKKQTKTSSK KNKKDESDDD VTDNSDISDD DNTGNSDISD
     DENDQEEDND ISSDEEETET RQKSSGKKGN VNKDVGSSRK LKTDKNARND NKVLEIRTTQ
     TGALKQVFER VSGVISDCCL TFMPADKDIN NAGDDNEYYE DESTKSSHKQ SKTTDRPKNT
     GGIRIIRLTE DNNTLVKVVL EAANFEYFRC DEPKITVGVD MHTLHSHLKM INDDDPIVIY
     MKKDIQGSLY IRSLSENNDN SEEREIELFL MDIINPEIPV PKTEFQNRIT MKSDKFHLIC
     KHLSQNSTFV EITSINNEIL FKGQSEGGKV TMTYKDTGYK KKEKPDQVIQ GVYELRNLLG
     FSKCNKLCNT IEIYLKNDFP LVLVISVATL GKMYVFLSPI DNGN