ID   PCNA_PICTO              Reviewed;         245 AA.
AC   Q6KZF1;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=DNA polymerase sliding clamp {ECO:0000255|HAMAP-Rule:MF_00317};
DE   AltName: Full=Proliferating cell nuclear antigen homolog {ECO:0000255|HAMAP-Rule:MF_00317};
DE            Short=PCNA {ECO:0000255|HAMAP-Rule:MF_00317};
GN   Name=pcn {ECO:0000255|HAMAP-Rule:MF_00317}; OrderedLocusNames=PTO1316;
OS   Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC
OS   100828).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC   Picrophilaceae; Picrophilus.
OX   NCBI_TaxID=263820;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828;
RX   PubMed=15184674; DOI=10.1073/pnas.0401356101;
RA   Fuetterer O., Angelov A., Liesegang H., Gottschalk G., Schleper C.,
RA   Schepers B., Dock C., Antranikian G., Liebl W.;
RT   "Genome sequence of Picrophilus torridus and its implications for life
RT   around pH 0.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9091-9096(2004).
CC   -!- FUNCTION: Sliding clamp subunit that acts as a moving platform for DNA
CC       processing. Responsible for tethering the catalytic subunit of DNA
CC       polymerase and other proteins to DNA during high-speed replication.
CC       {ECO:0000255|HAMAP-Rule:MF_00317}.
CC   -!- SUBUNIT: Homotrimer. The subunits circularize to form a toroid; DNA
CC       passes through its center. Replication factor C (RFC) is required to
CC       load the toroid on the DNA. {ECO:0000255|HAMAP-Rule:MF_00317}.
CC   -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00317}.
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DR   EMBL; AE017261; AAT43901.1; -; Genomic_DNA.
DR   RefSeq; WP_011178117.1; NC_005877.1.
DR   AlphaFoldDB; Q6KZF1; -.
DR   SMR; Q6KZF1; -.
DR   STRING; 263820.PTO1316; -.
DR   EnsemblBacteria; AAT43901; AAT43901; PTO1316.
DR   GeneID; 2845323; -.
DR   KEGG; pto:PTO1316; -.
DR   eggNOG; arCOG00488; Archaea.
DR   HOGENOM; CLU_043978_1_1_2; -.
DR   OMA; TIRKDPN; -.
DR   OrthoDB; 70433at2157; -.
DR   Proteomes; UP000000438; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00317; DNApol_clamp_arch; 1.
DR   InterPro; IPR000730; Pr_cel_nuc_antig.
DR   InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR   InterPro; IPR022659; Pr_cel_nuc_antig_CS.
DR   InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR   PANTHER; PTHR11352:SF0; PTHR11352:SF0; 1.
DR   Pfam; PF02747; PCNA_C; 1.
DR   Pfam; PF00705; PCNA_N; 1.
DR   PRINTS; PR00339; PCNACYCLIN.
DR   PROSITE; PS01251; PCNA_1; 1.
PE   3: Inferred from homology;
KW   DNA replication; DNA-binding; Reference proteome.
FT   CHAIN           1..245
FT                   /note="DNA polymerase sliding clamp"
FT                   /id="PRO_0000149202"
SQ   SEQUENCE   245 AA;  27086 MW;  778431021CC28A66 CRC64;
     MTRMSISVKN LKEIVDMLGT IVSEVKFKLE PNGISVTAVD PAHVAMISLD IPKNAFSEYD
     LDAPDEIAVD LDKVKSVIRL ASSNDTIVIS KDRDKLRFEI GTIIKSIALL DNNSVTTPRV
     PQINSDDYVI LSKSDLEKGL RAAEDVSDAI RLTLTPESFS AKSTSDSDES EMLLPKDMLK
     DISCSQPIKS SYPLEYLLKL VKSISSNEDI KISFKSDYPL SIEFSFNSET EPISGKFLLA
     PRMES