PCNA_POPNI
ID PCNA_POPNI Reviewed; 264 AA.
AC Q9MAY3;
DT 21-FEB-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=Proliferating cell nuclear antigen;
DE Short=PCNA;
GN Name=PCNA;
OS Populus nigra (Lombardy poplar).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX NCBI_TaxID=3691;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Nishiguchi M.;
RT "A cDNA clone encoding proliferating cell nuclear antigen (PCNA) from
RT lombardy poplar.";
RL Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is an auxiliary protein of DNA polymerase delta
CC and is involved in the control of eukaryotic DNA replication by
CC increasing the polymerase's processibility during elongation of the
CC leading strand. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000305}.
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DR EMBL; AB041506; BAA94512.1; -; mRNA.
DR AlphaFoldDB; Q9MAY3; -.
DR SMR; Q9MAY3; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR HAMAP; MF_00317; DNApol_clamp_arch; 1.
DR InterPro; IPR000730; Pr_cel_nuc_antig.
DR InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR InterPro; IPR022659; Pr_cel_nuc_antig_CS.
DR InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR Pfam; PF02747; PCNA_C; 1.
DR Pfam; PF00705; PCNA_N; 1.
DR PRINTS; PR00339; PCNACYCLIN.
DR TIGRFAMs; TIGR00590; pcna; 1.
DR PROSITE; PS01251; PCNA_1; 1.
DR PROSITE; PS00293; PCNA_2; 1.
PE 2: Evidence at transcript level;
KW DNA replication; DNA-binding; Nucleus.
FT CHAIN 1..264
FT /note="Proliferating cell nuclear antigen"
FT /id="PRO_0000149186"
FT DNA_BIND 61..80
FT /evidence="ECO:0000255"
SQ SEQUENCE 264 AA; 29139 MW; 85D20404ECF3B6D5 CRC64;
MLELRLVQGS LLKKVLESIK DLVNDANFDF SSSGFSLQSM DSSHVALVAL LLKSEGFEHY
RCDRNTSMGM NLGNMSKMLK CAGNDDIITI KGDDGSDTVT FMFESPTQDK IADFEMKLMD
IDSEHLGIPE AEYHAIVKMP SAEFARICKD LASIGDTVVI SVTKEGVKFS TRGDIGTANI
VLRQNTTVDK PEDATVIEMN EPVSMTFALR YMNSFTKATP LSNTVTISMS PDLPVVVEYK
IAEMGYVRFY LAPKMEEDEP EPGA