PCP14_ARATH
ID PCP14_ARATH Reviewed; 107 AA.
AC Q52K95;
DT 10-MAY-2017, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Precursor of CEP14 {ECO:0000303|PubMed:24179096};
DE Short=PCEP14 {ECO:0000303|PubMed:24179096};
DE Contains:
DE RecName: Full=C-terminally encoded peptide 14 {ECO:0000303|PubMed:24179096};
DE Short=CEP14 {ECO:0000303|PubMed:24179096};
DE Flags: Precursor;
GN Name=CEP14 {ECO:0000303|PubMed:24179096};
GN OrderedLocusNames=At1g29290 {ECO:0000312|Araport:AT1G29290};
GN ORFNames=F28N24.30 {ECO:0000312|EMBL:AEE31069.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT "Arabidopsis cDNA clones.";
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RC STRAIN=cv. Columbia;
RX PubMed=24179095; DOI=10.1093/jxb/ert331;
RA Roberts I., Smith S., De Rybel B., Van Den Broeke J., Smet W.,
RA De Cokere S., Mispelaere M., De Smet I., Beeckman T.;
RT "The CEP family in land plants: evolutionary analyses, expression studies,
RT and role in Arabidopsis shoot development.";
RL J. Exp. Bot. 64:5371-5381(2013).
RN [6]
RP INDUCTION BY OSMOTIC STRESS AND CARBON DIOXIDE, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=24179096; DOI=10.1093/jxb/ert332;
RA Delay C., Imin N., Djordjevic M.A.;
RT "CEP genes regulate root and shoot development in response to environmental
RT cues and are specific to seed plants.";
RL J. Exp. Bot. 64:5383-5394(2013).
CC -!- FUNCTION: Extracellular signaling peptide that may regulate primary
CC root growth rate and systemic nitrogen (N)-demand signaling.
CC {ECO:0000250|UniProtKB:Q8L8Y3}.
CC -!- SUBUNIT: Interacts with CEP receptors (e.g. CEPR1 and CEPR2).
CC {ECO:0000250|UniProtKB:Q8L8Y3}.
CC -!- SUBCELLULAR LOCATION: [C-terminally encoded peptide 14]: Secreted,
CC extracellular space, apoplast {ECO:0000250|UniProtKB:O80460}.
CC Note=Accumulates in xylem sap. {ECO:0000250|UniProtKB:O80460}.
CC -!- INDUCTION: Slightly repressed in roots by carbon dioxide CO(2). Induced
CC in shoots by osmotic stress (e.g. mannitol).
CC {ECO:0000269|PubMed:24179096}.
CC -!- PTM: The mature small signaling peptide is generated by proteolytic
CC processing of the longer precursor. {ECO:0000250|UniProtKB:Q8L8Y3}.
CC -!- SIMILARITY: Belongs to the C-terminally encoded plant signaling peptide
CC (CEP) family. {ECO:0000305}.
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DR EMBL; AC021043; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002684; AEE31069.1; -; Genomic_DNA.
DR EMBL; BT021973; AAY17410.1; -; mRNA.
DR EMBL; AK229062; BAF00944.1; -; mRNA.
DR RefSeq; NP_001319106.1; NM_001332843.1.
DR AlphaFoldDB; Q52K95; -.
DR STRING; 3702.AT1G29290.1; -.
DR PaxDb; Q52K95; -.
DR PRIDE; Q52K95; -.
DR EnsemblPlants; AT1G29290.1; AT1G29290.1; AT1G29290.
DR GeneID; 28717277; -.
DR Gramene; AT1G29290.1; AT1G29290.1; AT1G29290.
DR KEGG; ath:AT1G29290; -.
DR Araport; AT1G29290; -.
DR TAIR; locus:2029909; AT1G29290.
DR eggNOG; ENOG502S78T; Eukaryota.
DR HOGENOM; CLU_176522_0_0_1; -.
DR InParanoid; Q52K95; -.
DR OMA; AFAWSTE; -.
DR OrthoDB; 1536262at2759; -.
DR PhylomeDB; Q52K95; -.
DR PRO; PR:Q52K95; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q52K95; baseline and differential.
DR GO; GO:0048046; C:apoplast; ISS:UniProtKB.
DR GO; GO:0005179; F:hormone activity; ISS:UniProtKB.
DR GO; GO:0006995; P:cellular response to nitrogen starvation; IEA:InterPro.
DR GO; GO:1902025; P:nitrate import; ISS:UniProtKB.
DR GO; GO:2000280; P:regulation of root development; ISS:UniProtKB.
DR GO; GO:0010037; P:response to carbon dioxide; IEP:UniProtKB.
DR GO; GO:0006970; P:response to osmotic stress; IEP:UniProtKB.
DR InterPro; IPR038930; CEP13/CEP14.
DR PANTHER; PTHR37180; PTHR37180; 1.
PE 2: Evidence at transcript level;
KW Apoplast; Developmental protein; Glycoprotein; Hormone; Hydroxylation;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT PROPEP 22..92
FT /evidence="ECO:0000305"
FT /id="PRO_0000440012"
FT PEPTIDE 93..107
FT /note="C-terminally encoded peptide 14"
FT /evidence="ECO:0000250|UniProtKB:Q058G9"
FT /id="PRO_0000440013"
FT REGION 43..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 101
FT /note="Hydroxyproline"
FT /evidence="ECO:0000250|UniProtKB:Q058G9"
FT MOD_RES 103
FT /note="Hydroxyproline"
FT /evidence="ECO:0000250|UniProtKB:Q8L8Y3"
FT CARBOHYD 39
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 107 AA; 11762 MW; FA42C1A161844381 CRC64;
MAVRLIPTIW LFIVFAVIVS ALPSLVSSRK LLEVKKQENL TVREEEKSHM PHVTKTSTLS
ALPKGKIPNS TPSKKGHAAV FAGKLRSRHL STVDRYLRSV PSPGVGH
