PCR12_ARATH
ID PCR12_ARATH Reviewed; 161 AA.
AC Q9SX26; B2GVN4;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 03-MAY-2011, sequence version 2.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=Protein PLANT CADMIUM RESISTANCE 12;
DE Short=AtPCR12;
GN Name=PCR12; OrderedLocusNames=At1g68630; ORFNames=F24J5.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 69-161.
RC STRAIN=cv. Columbia;
RA de los Reyes C., Quan R., Chen H., Bautista V., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=20647347; DOI=10.1105/tpc.109.070185;
RA Song W.Y., Choi K.S., Kim do Y., Geisler M., Park J., Vincenzetti V.,
RA Schellenberg M., Kim S.H., Lim Y.P., Noh E.W., Lee Y., Martinoia E.;
RT "Arabidopsis PCR2 is a zinc exporter involved in both zinc extrusion and
RT long-distance zinc transport.";
RL Plant Cell 22:2237-2252(2010).
CC -!- FUNCTION: May be involved in heavy metals transport. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the cornifelin family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD49982.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC008075; AAD49982.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE34821.1; -; Genomic_DNA.
DR EMBL; BX813386; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; BT031380; ACB88836.1; -; mRNA.
DR PIR; G96710; G96710.
DR RefSeq; NP_177030.4; NM_105535.4.
DR AlphaFoldDB; Q9SX26; -.
DR STRING; 3702.AT1G68630.1; -.
DR PaxDb; Q9SX26; -.
DR PRIDE; Q9SX26; -.
DR ProteomicsDB; 236360; -.
DR EnsemblPlants; AT1G68630.1; AT1G68630.1; AT1G68630.
DR GeneID; 843193; -.
DR Gramene; AT1G68630.1; AT1G68630.1; AT1G68630.
DR KEGG; ath:AT1G68630; -.
DR Araport; AT1G68630; -.
DR TAIR; locus:2026905; AT1G68630.
DR eggNOG; ENOG502S00T; Eukaryota.
DR HOGENOM; CLU_083147_1_2_1; -.
DR InParanoid; Q9SX26; -.
DR OMA; EEPCRDF; -.
DR OrthoDB; 1354725at2759; -.
DR PRO; PR:Q9SX26; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SX26; baseline and differential.
DR Genevisible; Q9SX26; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR006461; PLAC_motif_containing.
DR PANTHER; PTHR15907; PTHR15907; 1.
DR Pfam; PF04749; PLAC8; 1.
DR TIGRFAMs; TIGR01571; A_thal_Cys_rich; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..161
FT /note="Protein PLANT CADMIUM RESISTANCE 12"
FT /id="PRO_0000407728"
FT TRANSMEM 71..89
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 80
FT /note="F -> L (in Ref. 3; BX813386)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 161 AA; 18037 MW; C4F4859B8309A8B9 CRC64;
MYGNGPVFKA EGTSFRDQPY AEQLPQGLWT TGLCDCHEDA HICVQTAIMP CVSFAQNVEI
VNRGTIPCMN AGLIHLALGF IGCSWLYAFP NRSRLREHFA LPEEPCRDFL VHLFCTPCAI
CQESRELKNR GADPSIGWLS NVEKWSREKV TPPIVVPGMI R
