ID   PCR3_ARATH              Reviewed;         152 AA.
AC   P0CW97; Q3E8N9;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   31-MAY-2011, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=Protein PLANT CADMIUM RESISTANCE 3;
DE            Short=AtPCR3;
GN   Name=PCR3; OrderedLocusNames=At5g35525; ORFNames=MOK9;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9872454; DOI=10.1093/dnares/5.5.297;
RA   Nakamura Y., Sato S., Asamizu E., Kaneko T., Kotani H., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. VII. Sequence
RT   features of the regions of 1,013,767 bp covered by sixteen physically
RT   assigned P1 and TAC clones.";
RL   DNA Res. 5:297-308(1998).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=15181212; DOI=10.1104/pp.103.037739;
RA   Song W.Y., Martinoia E., Lee J., Kim D., Kim D.Y., Vogt E., Shim D.,
RA   Choi K.S., Hwang I., Lee Y.;
RT   "A novel family of cys-rich membrane proteins mediates cadmium resistance
RT   in Arabidopsis.";
RL   Plant Physiol. 135:1027-1039(2004).
CC   -!- FUNCTION: May be involved in heavy metals transport. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the cornifelin family. {ECO:0000305}.
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DR   EMBL; AB015477; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002688; AED93976.1; -; Genomic_DNA.
DR   RefSeq; NP_680337.2; NM_148032.4.
DR   AlphaFoldDB; P0CW97; -.
DR   STRING; 3702.AT5G35525.1; -.
DR   TCDB; 1.A.87.3.2; the mechanosensitive calcium channel (mca) family.
DR   PaxDb; P0CW97; -.
DR   PRIDE; P0CW97; -.
DR   ProteomicsDB; 236802; -.
DR   EnsemblPlants; AT5G35525.1; AT5G35525.1; AT5G35525.
DR   GeneID; 833517; -.
DR   Gramene; AT5G35525.1; AT5G35525.1; AT5G35525.
DR   KEGG; ath:AT5G35525; -.
DR   Araport; AT5G35525; -.
DR   TAIR; locus:504954894; AT5G35525.
DR   eggNOG; ENOG502S7UD; Eukaryota.
DR   HOGENOM; CLU_083147_1_0_1; -.
DR   InParanoid; P0CW97; -.
DR   OMA; TAKEYGW; -.
DR   OrthoDB; 1354725at2759; -.
DR   PhylomeDB; P0CW97; -.
DR   PRO; PR:P0CW97; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; P0CW97; baseline and differential.
DR   Genevisible; P0CW97; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR006461; PLAC_motif_containing.
DR   PANTHER; PTHR15907; PTHR15907; 1.
DR   Pfam; PF04749; PLAC8; 1.
DR   TIGRFAMs; TIGR01571; A_thal_Cys_rich; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..152
FT                   /note="Protein PLANT CADMIUM RESISTANCE 3"
FT                   /id="PRO_0000407719"
FT   TRANSMEM        57..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   152 AA;  16473 MW;  3523B422241F3334 CRC64;
     MASQHLQANP HAEGEWSTGF CDCFSDCQNC CITWLCPCIT FGQVADIVDR GNTSCGTAGA
     LYVLLAAITG CGCLYSCIYR GKIRAQYNIR GDGCTDCLKH FCCELCALTQ EYRELKHRGF
     DMSLGWAGNV EKQQNQGGVA MGAPAFQGGM SR