PCX1_TAKRU
ID PCX1_TAKRU Reviewed; 1703 AA.
AC Q98UF7;
DT 03-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 61.
DE RecName: Full=Pecanex-like protein 1;
DE AltName: Full=Pecanex homolog protein 1 {ECO:0000250|UniProtKB:Q96RV3};
GN Name=pcnx1 {ECO:0000250|UniProtKB:Q96RV3}; Synonyms=pcnx, pcnxl1;
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Roux A.-F., Gasca S., Sanoudou D., Saridaki A., Ferraz C., Demaille J.,
RA Bagheri-Fam S., Ferguson-Smith M., Scherer G.;
RT "Cloning, mapping and expression of the neurogenic pecanex genes in
RT vertebrates: evidence of a new evolutionarily conserved gene family.";
RL Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the pecanex family. {ECO:0000305}.
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DR EMBL; AF154413; AAK13590.1; -; Genomic_DNA.
DR AlphaFoldDB; Q98UF7; -.
DR STRING; 31033.ENSTRUP00000029978; -.
DR eggNOG; KOG3604; Eukaryota.
DR InParanoid; Q98UF7; -.
DR Proteomes; UP000005226; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR039797; Pecanex.
DR InterPro; IPR007735; Pecanex_C.
DR PANTHER; PTHR12372; PTHR12372; 3.
DR Pfam; PF05041; Pecanex_C; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..1703
FT /note="Pecanex-like protein 1"
FT /id="PRO_0000215795"
FT TRANSMEM 31..53
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 57..74
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 416..438
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 477..499
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 525..547
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 569..591
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 603..622
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 675..697
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 704..721
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 91..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1475..1556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1577..1598
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 256
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 564
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 988
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 1129
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 1391
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 1622
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 1703 AA; 191348 MW; 4FBCD553EE81DEDC CRC64;
MGSQTLQILR QGVWASVTGG WYYDPDQNTF VNALHLYIWL FLLCFPFTLY MALQPSMVIV
GIYCGVIAAM FLLLKTVNYR LHHALDEGEV VEHQTRESKG SRGGTGGAND PVTRREDSNG
LGDPGGGIEM ADFIRQETPP VDCSSRNSYV GMDLNQRMSS THGRTTVAKA PGSEETVIFR
RERSTFRRQA VRRRHNAGSN PTPPTSLIGS PLRYALHEAD RPSGVRSWYR TVKSQPSRTP
SQVTVLSTSA SLLARNGSTH LEGSQDKAST VGTTSLQDEF GTLTPSLYEI RGCHIGLGNF
ESATRRASNN IWDTDSHLSS STSVRFYPHD LISLHHIRAN RLLTMDPELL EQQDDLSPDL
QDAPLGQDNP SAASAAGKTR QYYRLWLLPF LWVGLHFDRL TLLALFDRNR EVLENVLAVV
LAVLVAFLGS VLLIHGFFAD IWVFQFCLVI ASCQYSLLKS VQPDSSSPRH GHNRIIAYSR
PVYFCLCCGL IWLLHYGSLR TTSSRFTLYG VALTSSLVLA SARDLVIVFT LCFPIIFFVG
LLPQVNTFVM YLFEQLDIHV FGGNASTSLL SALYSILRSI VTVALLYCFC YGALKENWEP
HHIPVLFSVF CGLLVAVSYH LSRQSSDPSV LMYVPLSKVF PQLRSKNPED PLSEVQDPLP
EKLRASVNER LQSDLIVCVV IAVLYFAIHV STVFIALQPY LSYVLYGLLG AVGLLTHYLL
PQLRKQLPWY CFSHPLLKTK EYYQFEVRDA AHVMWFEKFH VWLLFVEKNV LYPLVILNEL
SGSARELASP KRLDTEVGAL MITVAGLKLL RSSYSSPTYQ YITILFTVLF FTLDHRHLSE
TLLLDLFLMS IIFSKMWELF YKLHFVYTYI APWQITWGSA FHAFAQPFAV PHSAMLFVQA
VVSSIFSTPL NPFLGSAIFI TSYVRPVKFW ERDYNTKRVD HSNTRLASQL DRNPGSDDNN
LNSIFYEHLT RSLQHSLCGD LLLGRWGNFS TGDCFILASD YLNALVHLIE IGNGLVTFQL
RGLEFRGTYC QQREVEAITE GVEEDEGCCC CEPGHLPHIL SFNAAFGQRW LAWEVVVTKY
VLEGYSITDN SAASMLQVFE LRRILTTYYV KGIIYYVIAS PKLEEWLAND TMKEGLRGCS
ERNYVDLDAT FNPNIDEDYD HRLSGISRDS FCGVYLGWIQ YCNSRRTKPL DSEKDSALVL
LCFGLCVLGR RALGTAAHQM SSNLESFLYG LHALFKGDFR ISSVRDEWIF ADMELLRKVV
VPGIRMSLKL HQDHFTSPDE YDEPAVLFEA ISTHQQNLVI AHEGDPAWRS AVLSNAPSLL
ALRHVLDEGT NEYKIIMLNR RYLSFRVIKV NKECVRGLWA GQQQELVFLR NRNPERGSIQ
NAKQALRNMI NSSCDQPIGY PIYVSPLTTS YCNSHPQLRH ILGGPISFGN IRNFVVSTWH
RLRKGCGAGC NSGGNIEDSD AGGLSCGTSQ SSQSVQSGLV RHSPARASVV SQSSSYRYSS
SRHSSLRTST TGLEPCRRSS TSQLSLRTLP TSLQLRLGST SDPAGPSSSL SSHSIPPCKR
HTLVGLLGND GLCSTVTDPL SQHHHPHHHP QQHNPTHATV RRDDISYRVQ IVDVGQVLEN
INLSKRKELQ WPDDAMRHKA GRTCWRDWSP LEGMEGHVIH RWVPCSRDPG SRSHIDKTIL
LVQVEDKIVP IIETGVIELG AEV