ID   PCXA_TRIEI              Reviewed;         477 AA.
AC   Q10YZ5;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Proton extrusion protein PcxA {ECO:0000255|HAMAP-Rule:MF_01308};
GN   Name=pcxA {ECO:0000255|HAMAP-Rule:MF_01308}; OrderedLocusNames=Tery_3436;
OS   Trichodesmium erythraeum (strain IMS101).
OC   Bacteria; Cyanobacteria; Oscillatoriophycideae; Oscillatoriales;
OC   Microcoleaceae; Trichodesmium.
OX   NCBI_TaxID=203124;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IMS101;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Kiss H., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA   Richardson P.;
RT   "Complete sequence of Trichodesmium erythraeum IMS101.";
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in light-induced Na(+)-dependent proton extrusion.
CC       Also seems to be involved in CO(2) transport. {ECO:0000255|HAMAP-
CC       Rule:MF_01308}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01308}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01308}.
CC   -!- SIMILARITY: Belongs to the Cema family. {ECO:0000305}.
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DR   EMBL; CP000393; ABG52529.1; -; Genomic_DNA.
DR   RefSeq; WP_011612872.1; NC_008312.1.
DR   AlphaFoldDB; Q10YZ5; -.
DR   SMR; Q10YZ5; -.
DR   STRING; 203124.Tery_3436; -.
DR   EnsemblBacteria; ABG52529; ABG52529; Tery_3436.
DR   KEGG; ter:Tery_3436; -.
DR   eggNOG; ENOG502Z8DN; Bacteria.
DR   HOGENOM; CLU_690401_0_0_3; -.
DR   OMA; PANRDFI; -.
DR   OrthoDB; 1605855at2; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015078; F:proton transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01308; CemA; 1.
DR   InterPro; IPR004282; CemA.
DR   PANTHER; PTHR33650; PTHR33650; 1.
DR   Pfam; PF03040; CemA; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Hydrogen ion transport; Ion transport;
KW   Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..477
FT                   /note="Proton extrusion protein PcxA"
FT                   /id="PRO_0000293506"
FT   TRANSMEM        239..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        354..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
FT   TRANSMEM        437..457
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01308"
SQ   SEQUENCE   477 AA;  55245 MW;  511611B171EA1BBE CRC64;
     MAISPWKQFK LSVLNANQWF RKTPERALNM AYDAANKIRS IEEEHFEGRK ISNVSISYSN
     STKSYFNSQL NRYLKIIQVR LAEFNTSISV VGTLDQNKVD KQKDKFDQNY QQEFPGRSSI
     ILDKLEFIDQ VSSRYYKSSN HEAQELNTDL EIPHSSSSIA IVSSNVNVNN YPNNVRAGSS
     QNQNNLAELK SNIPNTNFLP RSLLKTFKKI KQELDPEAET EVIRKFRKSQ IKTLTSVRFI
     LLVILVPLLI HQLSKITFVG YLVDNFMSLP HQQAELFLNS NMEEEALVKL HQYEEKLHFK
     MYLGQAPELF PELYESGKEI TEIPKSEREE LIEHKVEKKA QEIALEYKAK GNNGIKNIFC
     DFISLITFVI IISTRKRELE VLKSFMDDVV YGLSDSAKAF IIILLTDMFV GFHSPHGWEV
     ILENITRHFG LPESRDFNFL FIATFPVILD AVFKYWIFRY LNRSSPSAVA TYKNMNE