ID   PCYA_PARMW              Reviewed;         247 AA.
AC   Q7U7A1;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Phycocyanobilin:ferredoxin oxidoreductase;
DE            EC=1.3.7.5;
GN   Name=pcyA; OrderedLocusNames=SYNW1084;
OS   Parasynechococcus marenigrum (strain WH8102).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Parasynechococcus; Parasynechococcus marenigrum.
OX   NCBI_TaxID=84588;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WH8102;
RX   PubMed=12917641; DOI=10.1038/nature01943;
RA   Palenik B., Brahamsha B., Larimer F.W., Land M.L., Hauser L., Chain P.,
RA   Lamerdin J.E., Regala W., Allen E.E., McCarren J., Paulsen I.T.,
RA   Dufresne A., Partensky F., Webb E.A., Waterbury J.;
RT   "The genome of a motile marine Synechococcus.";
RL   Nature 424:1037-1042(2003).
CC   -!- FUNCTION: Catalyzes the four-electron reduction of biliverdin IX-alpha
CC       (2-electron reduction at both the A and D rings); the reaction proceeds
CC       via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin.
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R,3Z)-phycocyanobilin + 4 oxidized [2Fe-2S]-[ferredoxin] =
CC         biliverdin IXalpha + 4 H(+) + 4 reduced [2Fe-2S]-[ferredoxin];
CC         Xref=Rhea:RHEA:15309, Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:33737, ChEBI:CHEBI:33738,
CC         ChEBI:CHEBI:57437, ChEBI:CHEBI:57991; EC=1.3.7.5;
CC   -!- SIMILARITY: Belongs to the HY2 family. {ECO:0000305}.
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DR   EMBL; BX569692; CAE07599.1; -; Genomic_DNA.
DR   RefSeq; WP_011127949.1; NC_005070.1.
DR   AlphaFoldDB; Q7U7A1; -.
DR   SMR; Q7U7A1; -.
DR   STRING; 84588.SYNW1084; -.
DR   EnsemblBacteria; CAE07599; CAE07599; SYNW1084.
DR   KEGG; syw:SYNW1084; -.
DR   eggNOG; ENOG502Z7RN; Bacteria.
DR   HOGENOM; CLU_074224_0_0_3; -.
DR   OMA; YQTPQFR; -.
DR   OrthoDB; 1105902at2; -.
DR   Proteomes; UP000001422; Chromosome.
DR   GO; GO:0050897; F:cobalt ion binding; IEA:InterPro.
DR   GO; GO:0050620; F:phycocyanobilin:ferredoxin oxidoreductase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0010024; P:phytochromobilin biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_00618; Ferredoxin_bilin_red; 1.
DR   InterPro; IPR009249; Ferredoxin-dep_bilin_Rdtase.
DR   InterPro; IPR022870; Ferredoxin_bilin_OxRdtase.
DR   PANTHER; PTHR34557; PTHR34557; 1.
DR   Pfam; PF05996; Fe_bilin_red; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..247
FT                   /note="Phycocyanobilin:ferredoxin oxidoreductase"
FT                   /id="PRO_0000216746"
SQ   SEQUENCE   247 AA;  27004 MW;  45BB3FFE058D89A4 CRC64;
     MQSPPSESSS TVAPLIPSLA ETIRGAWIGL PELKPLDADS DFSSIEGQLE GDDLLIRNEL
     LCCRGVRKIH LELARLGRGL QILHCVWFPD PRFDLPIFGA DIVAGPAGVS AAIVDLSPVS
     GTLPSGIETA LAGTPSPAFR QVRDLPGWGT IFSPHVCFIR PDGAEEEVLF RSRVEEVLTI
     LRTAVLQTAC EPATAASTIR RYEGQLSYCL QQKRNDKTRR VLEKAFDASW ADRYIEELLF
     DDPLPPG