ID   PCYA_RIPO1              Reviewed;         245 AA.
AC   B7JWS2;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Phycocyanobilin:ferredoxin oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00618};
DE            EC=1.3.7.5 {ECO:0000255|HAMAP-Rule:MF_00618};
GN   Name=pcyA {ECO:0000255|HAMAP-Rule:MF_00618};
GN   OrderedLocusNames=PCC8801_1724;
OS   Rippkaea orientalis (strain PCC 8801) (Cyanothece sp. (strain PCC 8801)).
OC   Bacteria; Cyanobacteria; Oscillatoriophycideae; Chroococcales;
OC   Aphanothecaceae; Rippkaea; Rippkaea orientalis.
OX   NCBI_TaxID=41431;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 8801;
RX   PubMed=21972240; DOI=10.1128/mbio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA   Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT   unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
CC   -!- FUNCTION: Catalyzes the four-electron reduction of biliverdin IX-alpha
CC       (2-electron reduction at both the A and D rings); the reaction proceeds
CC       via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin.
CC       {ECO:0000255|HAMAP-Rule:MF_00618}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R,3Z)-phycocyanobilin + 4 oxidized [2Fe-2S]-[ferredoxin] =
CC         biliverdin IXalpha + 4 H(+) + 4 reduced [2Fe-2S]-[ferredoxin];
CC         Xref=Rhea:RHEA:15309, Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:33737, ChEBI:CHEBI:33738,
CC         ChEBI:CHEBI:57437, ChEBI:CHEBI:57991; EC=1.3.7.5;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00618};
CC   -!- SIMILARITY: Belongs to the HY2 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00618}.
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DR   EMBL; CP001287; ACK65771.1; -; Genomic_DNA.
DR   RefSeq; WP_012595044.1; NC_011726.1.
DR   AlphaFoldDB; B7JWS2; -.
DR   SMR; B7JWS2; -.
DR   STRING; 41431.PCC8801_1724; -.
DR   EnsemblBacteria; ACK65771; ACK65771; PCC8801_1724.
DR   KEGG; cyp:PCC8801_1724; -.
DR   eggNOG; ENOG502Z7RN; Bacteria.
DR   HOGENOM; CLU_074224_0_0_3; -.
DR   OMA; YQTPQFR; -.
DR   OrthoDB; 1105902at2; -.
DR   Proteomes; UP000008204; Chromosome.
DR   GO; GO:0050897; F:cobalt ion binding; IEA:InterPro.
DR   GO; GO:0050620; F:phycocyanobilin:ferredoxin oxidoreductase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0010024; P:phytochromobilin biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_00618; Ferredoxin_bilin_red; 1.
DR   InterPro; IPR009249; Ferredoxin-dep_bilin_Rdtase.
DR   InterPro; IPR022870; Ferredoxin_bilin_OxRdtase.
DR   PANTHER; PTHR34557; PTHR34557; 1.
DR   Pfam; PF05996; Fe_bilin_red; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..245
FT                   /note="Phycocyanobilin:ferredoxin oxidoreductase"
FT                   /id="PRO_1000130440"
SQ   SEQUENCE   245 AA;  27944 MW;  5D584C1DE543A2AB CRC64;
     MLDTSPVSIR SQLNPLICQL AEVILSHWQE YLSLSLYKLP DGLGYVEGKL EGERLVIENR
     CYQAPQFRKM HLELAKVGKG LDILHCVMFP NPDYSLPMFG CDIVANSRAV SAAIADLSPA
     NAELTLSPTY QKALSQLPSL DFRESRDLPE WGDIFSEYCL FIRPTNAEEE TQFINRVADF
     LKIHCQLAVQ SQPVSVEQET LNLAGQKYYC TKQQQNDKTR RVLEKAFGQE WADKYITQVL
     FDLPY