ID   PCYA_THEVB              Reviewed;         236 AA.
AC   P59288;
DT   12-FEB-2003, integrated into UniProtKB/Swiss-Prot.
DT   12-FEB-2003, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Phycocyanobilin:ferredoxin oxidoreductase;
DE            EC=1.3.7.5;
GN   Name=pcyA; OrderedLocusNames=tll2308;
OS   Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1).
OC   Bacteria; Cyanobacteria; Pseudanabaenales; Thermosynechococcaceae;
OC   Thermosynechococcus.
OX   NCBI_TaxID=197221;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIES-2133 / IAM M-273 / BP-1;
RX   PubMed=12240834; DOI=10.1093/dnares/9.4.123;
RA   Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S.,
RA   Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C.,
RA   Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takeuchi C., Yamada M., Tabata S.;
RT   "Complete genome structure of the thermophilic cyanobacterium
RT   Thermosynechococcus elongatus BP-1.";
RL   DNA Res. 9:123-130(2002).
CC   -!- FUNCTION: Catalyzes the four-electron reduction of biliverdin IX-alpha
CC       (2-electron reduction at both the A and D rings); the reaction proceeds
CC       via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin.
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R,3Z)-phycocyanobilin + 4 oxidized [2Fe-2S]-[ferredoxin] =
CC         biliverdin IXalpha + 4 H(+) + 4 reduced [2Fe-2S]-[ferredoxin];
CC         Xref=Rhea:RHEA:15309, Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:33737, ChEBI:CHEBI:33738,
CC         ChEBI:CHEBI:57437, ChEBI:CHEBI:57991; EC=1.3.7.5;
CC   -!- SIMILARITY: Belongs to the HY2 family. {ECO:0000305}.
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DR   EMBL; BA000039; BAC09860.1; -; Genomic_DNA.
DR   RefSeq; NP_683098.1; NC_004113.1.
DR   RefSeq; WP_011058141.1; NC_004113.1.
DR   AlphaFoldDB; P59288; -.
DR   SMR; P59288; -.
DR   IntAct; P59288; 1.
DR   MINT; P59288; -.
DR   STRING; 197221.22296035; -.
DR   EnsemblBacteria; BAC09860; BAC09860; BAC09860.
DR   KEGG; tel:tll2308; -.
DR   PATRIC; fig|197221.4.peg.2417; -.
DR   eggNOG; ENOG502Z7RN; Bacteria.
DR   OMA; YQTPQFR; -.
DR   OrthoDB; 1105902at2; -.
DR   Proteomes; UP000000440; Chromosome.
DR   GO; GO:0050897; F:cobalt ion binding; IEA:InterPro.
DR   GO; GO:0050620; F:phycocyanobilin:ferredoxin oxidoreductase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0010024; P:phytochromobilin biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_00618; Ferredoxin_bilin_red; 1.
DR   InterPro; IPR009249; Ferredoxin-dep_bilin_Rdtase.
DR   InterPro; IPR022870; Ferredoxin_bilin_OxRdtase.
DR   PANTHER; PTHR34557; PTHR34557; 1.
DR   Pfam; PF05996; Fe_bilin_red; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..236
FT                   /note="Phycocyanobilin:ferredoxin oxidoreductase"
FT                   /id="PRO_0000216744"
SQ   SEQUENCE   236 AA;  26930 MW;  359338886E898FBD CRC64;
     MSLRQHQHPL IQRLADRIEA IWQAFFPLAP YALPEDLGYV EGKLEGERLT IENHCYQAPP
     FRKLHLELAR VGESLDILHC VMFPEPRYDL PMFGCDLVGG RGQISAAIVD LSPVTGQLPA
     AYTCALNALP KLTFRQPREL PPWGHIFSPF CIFIRPQGEA EEQQFLDRIG EYLTLHCQLS
     QQAVPTDHPQ AVIAGQRQYC QQQQQNDKTR RVLEKAFGVP WAERYMTTVL FDVPPV