PCYA_TRIEI
ID PCYA_TRIEI Reviewed; 245 AA.
AC Q10X61;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2006, sequence version 1.
DT 25-MAY-2022, entry version 82.
DE RecName: Full=Phycocyanobilin:ferredoxin oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00618};
DE EC=1.3.7.5 {ECO:0000255|HAMAP-Rule:MF_00618};
GN Name=pcyA {ECO:0000255|HAMAP-Rule:MF_00618}; OrderedLocusNames=Tery_4156;
OS Trichodesmium erythraeum (strain IMS101).
OC Bacteria; Cyanobacteria; Oscillatoriophycideae; Oscillatoriales;
OC Microcoleaceae; Trichodesmium.
OX NCBI_TaxID=203124;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMS101;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Kiss H., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P.,
RA Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA Richardson P.;
RT "Complete sequence of Trichodesmium erythraeum IMS101.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the four-electron reduction of biliverdin IX-alpha
CC (2-electron reduction at both the A and D rings); the reaction proceeds
CC via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin.
CC {ECO:0000255|HAMAP-Rule:MF_00618}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(2R,3Z)-phycocyanobilin + 4 oxidized [2Fe-2S]-[ferredoxin] =
CC biliverdin IXalpha + 4 H(+) + 4 reduced [2Fe-2S]-[ferredoxin];
CC Xref=Rhea:RHEA:15309, Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:33737, ChEBI:CHEBI:33738,
CC ChEBI:CHEBI:57437, ChEBI:CHEBI:57991; EC=1.3.7.5;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00618};
CC -!- SIMILARITY: Belongs to the HY2 family. {ECO:0000255|HAMAP-
CC Rule:MF_00618}.
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DR EMBL; CP000393; ABG53163.1; -; Genomic_DNA.
DR RefSeq; WP_011613493.1; NC_008312.1.
DR AlphaFoldDB; Q10X61; -.
DR SMR; Q10X61; -.
DR STRING; 203124.Tery_4156; -.
DR EnsemblBacteria; ABG53163; ABG53163; Tery_4156.
DR KEGG; ter:Tery_4156; -.
DR eggNOG; ENOG502Z7RN; Bacteria.
DR HOGENOM; CLU_074224_0_0_3; -.
DR OMA; YQTPQFR; -.
DR OrthoDB; 1105902at2; -.
DR GO; GO:0050897; F:cobalt ion binding; IEA:InterPro.
DR GO; GO:0050620; F:phycocyanobilin:ferredoxin oxidoreductase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0010024; P:phytochromobilin biosynthetic process; IEA:InterPro.
DR HAMAP; MF_00618; Ferredoxin_bilin_red; 1.
DR InterPro; IPR009249; Ferredoxin-dep_bilin_Rdtase.
DR InterPro; IPR022870; Ferredoxin_bilin_OxRdtase.
DR PANTHER; PTHR34557; PTHR34557; 1.
DR Pfam; PF05996; Fe_bilin_red; 1.
PE 3: Inferred from homology;
KW Oxidoreductase.
FT CHAIN 1..245
FT /note="Phycocyanobilin:ferredoxin oxidoreductase"
FT /id="PRO_1000061379"
SQ SEQUENCE 245 AA; 28277 MW; 734F17725680DD70 CRC64;
MLKTSIPSQG IQQNPLVCQL ANSIEAVWQR YLNLEPYYLP ADLGYVEGRL EGEKLIIQNK
CYQTAQFRKL HLELATIGPK LDILHCVMFP RISYPLPIFG TDLVGARGQI SAAVVDISPQ
SQDRKLPEVY NYQLQALPIK EFAHPRQLPQ WGEIFSEFCL FIRPTGLEEE QKFISIVESY
LEIHCQQAIA QKPVSPEQQL EILKAQHHYC TQQRQNDKTR RVLEKAFGPE WTDYYLTTVL
FDSPN