ID   PCYA_TRIV2              Reviewed;         245 AA.
AC   Q3M745;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Phycocyanobilin:ferredoxin oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00618};
DE            EC=1.3.7.5 {ECO:0000255|HAMAP-Rule:MF_00618};
GN   Name=pcyA {ECO:0000255|HAMAP-Rule:MF_00618}; OrderedLocusNames=Ava_3585;
OS   Trichormus variabilis (strain ATCC 29413 / PCC 7937) (Anabaena variabilis).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Trichormus.
OX   NCBI_TaxID=240292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29413 / PCC 7937;
RX   PubMed=25197444; DOI=10.4056/sigs.3899418;
RA   Thiel T., Pratte B.S., Zhong J., Goodwin L., Copeland A., Lucas S., Han C.,
RA   Pitluck S., Land M.L., Kyrpides N.C., Woyke T.;
RT   "Complete genome sequence of Anabaena variabilis ATCC 29413.";
RL   Stand. Genomic Sci. 9:562-573(2014).
CC   -!- FUNCTION: Catalyzes the four-electron reduction of biliverdin IX-alpha
CC       (2-electron reduction at both the A and D rings); the reaction proceeds
CC       via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin.
CC       {ECO:0000255|HAMAP-Rule:MF_00618}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R,3Z)-phycocyanobilin + 4 oxidized [2Fe-2S]-[ferredoxin] =
CC         biliverdin IXalpha + 4 H(+) + 4 reduced [2Fe-2S]-[ferredoxin];
CC         Xref=Rhea:RHEA:15309, Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:33737, ChEBI:CHEBI:33738,
CC         ChEBI:CHEBI:57437, ChEBI:CHEBI:57991; EC=1.3.7.5;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00618};
CC   -!- SIMILARITY: Belongs to the HY2 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00618}.
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DR   EMBL; CP000117; ABA23191.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q3M745; -.
DR   SMR; Q3M745; -.
DR   STRING; 240292.Ava_3585; -.
DR   PRIDE; Q3M745; -.
DR   EnsemblBacteria; ABA23191; ABA23191; Ava_3585.
DR   KEGG; ava:Ava_3585; -.
DR   eggNOG; ENOG502Z7RN; Bacteria.
DR   HOGENOM; CLU_074224_0_0_3; -.
DR   OMA; YQTPQFR; -.
DR   Proteomes; UP000002533; Chromosome.
DR   GO; GO:0050897; F:cobalt ion binding; IEA:InterPro.
DR   GO; GO:0050620; F:phycocyanobilin:ferredoxin oxidoreductase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0010024; P:phytochromobilin biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_00618; Ferredoxin_bilin_red; 1.
DR   InterPro; IPR009249; Ferredoxin-dep_bilin_Rdtase.
DR   InterPro; IPR022870; Ferredoxin_bilin_OxRdtase.
DR   PANTHER; PTHR34557; PTHR34557; 1.
DR   Pfam; PF05996; Fe_bilin_red; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..245
FT                   /note="Phycocyanobilin:ferredoxin oxidoreductase"
FT                   /id="PRO_1000061374"
SQ   SEQUENCE   245 AA;  27940 MW;  2CD7B09C98839881 CRC64;
     MSLTSIPSLR EQQHPLIRQL ADCIEEVWHQ HLDLSPYHLP AELGYVEGRL EGEKLTIENR
     CYQTPQFRKM HLELAKVGNM LDILHCVMFP RPEYDLPMFG CDLVGGRGQI SAAIADLSPV
     HLDRTLPASY NSALTNLDTL NFSQPRELPE WGNIFSDFCI FVRPSSPEEE AMFLGRVREF
     LQVHCQGAIA ASPVSAEQKQ HILAGQHNYC SKQQQNDKTR RVLEKAFGTD WAENYMTTVL
     FDLPE